Strain profiling and epidemiology of bacterial species from metagenomic sequencing

Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.

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Autores principales:	Davide Albanese, Claudio Donati
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bbdd0bfb3791437cb7966ed2a7f18272
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spelling	oai:doaj.org-article:bbdd0bfb3791437cb7966ed2a7f182722021-12-02T17:06:06ZStrain profiling and epidemiology of bacterial species from metagenomic sequencing10.1038/s41467-017-02209-52041-1723https://doaj.org/article/bbdd0bfb3791437cb7966ed2a7f182722017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02209-5https://doaj.org/toc/2041-1723Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.Davide AlbaneseClaudio DonatiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Davide Albanese Claudio Donati Strain profiling and epidemiology of bacterial species from metagenomic sequencing
description	Microbiota is often a complex mixture of multiple coexisting species and strains with high level of phenotypic and genomic variability. Here, Albanese and Donati develop StrainEst for estimating the number and identity of coexisting strains and their relative abundances in mixed metagenomic samples.
format	article
author	Davide Albanese Claudio Donati
author_facet	Davide Albanese Claudio Donati
author_sort	Davide Albanese
title	Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_short	Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_full	Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_fullStr	Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_full_unstemmed	Strain profiling and epidemiology of bacterial species from metagenomic sequencing
title_sort	strain profiling and epidemiology of bacterial species from metagenomic sequencing
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bbdd0bfb3791437cb7966ed2a7f18272
work_keys_str_mv	AT davidealbanese strainprofilingandepidemiologyofbacterialspeciesfrommetagenomicsequencing AT claudiodonati strainprofilingandepidemiologyofbacterialspeciesfrommetagenomicsequencing
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Strain profiling and epidemiology of bacterial species from metagenomic sequencing

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