Suppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cells.

Suppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cells.

<h4>Background</h4>Although p75 neurotrophin receptor (p75NTR) is the first neurotrophin receptor isolated, its diverse physiological functions and signaling have remained elusive for many years. Loss-of-function phenotypic analyses for p75NTR were mainly focused at the genetic level; ho...

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Autores principales: Congcong Zhang, Saskia Helmsing, Marta Zagrebelsky, Thomas Schirrmann, Andrea L J Marschall, Manuela Schüngel, Martin Korte, Michael Hust, Stefan Dübel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bbdf33d0bd4b4812a00661f348dc3479
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