Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections

Aim. To identify the state of phagocytic and oxidative activity of phagocytes in the blood in patients with reactive arthritis caused by chlamydia and viral infections. Material and Methods. The investigation involved 97 patients with reactive arthritis (33 patients with reactive arthritis and EB...

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Autores principales:	M.P. Lomikovska, I.Y. Kril, V.V. Chopyak
Formato:	article
Lenguaje:	EN UK
Publicado:	Danylo Halytsky Lviv National Medical University 2019
Materias:	reactive arthritis, epstein-barr virus, chlamydia trachomatis, autoimmune diseases Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bbedb91b6dca418faad386ab1e799139
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spelling	oai:doaj.org-article:bbedb91b6dca418faad386ab1e7991392021-11-10T19:49:51ZPhagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections1029-42442415-330310.25040/aml2019.04.030https://doaj.org/article/bbedb91b6dca418faad386ab1e7991392019-12-01T00:00:00Zhttps://amljournal.com/index.php/journal/article/view/48https://doaj.org/toc/1029-4244https://doaj.org/toc/2415-3303Aim. To identify the state of phagocytic and oxidative activity of phagocytes in the blood in patients with reactive arthritis caused by chlamydia and viral infections. Material and Methods. The investigation involved 97 patients with reactive arthritis (33 patients with reactive arthritis and EBV; 19 patients with reactive arthritis and dual infection - EBV and C. trachomatis; 28 patients with reactive arthritis and C. trachomatis; and 17 patients with reactive arthritis induced by tonsillitis). The study of phagocytic activity and "oxidative explosion" of neutrophils and monocytes was conducted using the technique of flow cytofluorometry. Results and Discussion. Neutrophil phagocytic activity after E.coli stimulation was reduced (p<0.05) in patients with reactive arthritis with EBV and C. trachomatis compared to the group of healthy individuals. Phagocytic activity of monocytes after E. coli stimulation was reduced in patients with reactive arthritis with EBV, EBV and C. trachomatis, and C.trachomatis compared to the group of healthy individuals. The oxidative activity of neutrophils after E. coli stimulation was reduced in the group of patients with reactive arthritis and combined infection - EBV and C Trachomatis. Conclusions. In the blood of patients with reactive arthritis changes in the phagocytic activity of neutrophils and monocytes without stimulation and a decrease in their oxidative activity after E.coli stimulation were observed.M.P. LomikovskaI.Y. KrilV.V. ChopyakDanylo Halytsky Lviv National Medical Universityarticlereactive arthritis, epstein-barr virus, chlamydia trachomatis, autoimmune diseasesMedicine (General)R5-920ENUKActa Medica Leopoliensia, Vol 25, Iss 4, Pp 30-35 (2019)
institution	DOAJ
collection	DOAJ
language	EN UK
topic	reactive arthritis, epstein-barr virus, chlamydia trachomatis, autoimmune diseases Medicine (General) R5-920
spellingShingle	reactive arthritis, epstein-barr virus, chlamydia trachomatis, autoimmune diseases Medicine (General) R5-920 M.P. Lomikovska I.Y. Kril V.V. Chopyak Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
description	Aim. To identify the state of phagocytic and oxidative activity of phagocytes in the blood in patients with reactive arthritis caused by chlamydia and viral infections. Material and Methods. The investigation involved 97 patients with reactive arthritis (33 patients with reactive arthritis and EBV; 19 patients with reactive arthritis and dual infection - EBV and C. trachomatis; 28 patients with reactive arthritis and C. trachomatis; and 17 patients with reactive arthritis induced by tonsillitis). The study of phagocytic activity and "oxidative explosion" of neutrophils and monocytes was conducted using the technique of flow cytofluorometry. Results and Discussion. Neutrophil phagocytic activity after E.coli stimulation was reduced (p<0.05) in patients with reactive arthritis with EBV and C. trachomatis compared to the group of healthy individuals. Phagocytic activity of monocytes after E. coli stimulation was reduced in patients with reactive arthritis with EBV, EBV and C. trachomatis, and C.trachomatis compared to the group of healthy individuals. The oxidative activity of neutrophils after E. coli stimulation was reduced in the group of patients with reactive arthritis and combined infection - EBV and C Trachomatis. Conclusions. In the blood of patients with reactive arthritis changes in the phagocytic activity of neutrophils and monocytes without stimulation and a decrease in their oxidative activity after E.coli stimulation were observed.
format	article
author	M.P. Lomikovska I.Y. Kril V.V. Chopyak
author_facet	M.P. Lomikovska I.Y. Kril V.V. Chopyak
author_sort	M.P. Lomikovska
title	Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
title_short	Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
title_full	Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
title_fullStr	Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
title_full_unstemmed	Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections
title_sort	phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by epstein-barr viral and chlamydial infections
publisher	Danylo Halytsky Lviv National Medical University
publishDate	2019
url	https://doaj.org/article/bbedb91b6dca418faad386ab1e799139
work_keys_str_mv	AT mplomikovska phagocyticactivityofneutrophilsandmonocytesinpatientswithreactivearthritiscausedbyepsteinbarrviralandchlamydialinfections AT iykril phagocyticactivityofneutrophilsandmonocytesinpatientswithreactivearthritiscausedbyepsteinbarrviralandchlamydialinfections AT vvchopyak phagocyticactivityofneutrophilsandmonocytesinpatientswithreactivearthritiscausedbyepsteinbarrviralandchlamydialinfections
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Phagocytic activity of neutrophils and monocytes in patients with reactive arthritis caused by Epstein-Barr viral and chlamydial infections

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