Molecular characteristics of Neisseria meningitidis in Qatar

Abstract The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to...

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Autores principales: Manal Mahmoud Hamed, Fayaz Ahmad Mir, Emad Bashier Ibrahim Elmagboul, Abdullatif Al-Khal, Muna A. Rahman S. Al. Maslamani, Anand Sarwottam Deshmukh, Hamad Eid Al-Romaihi, Mohd. Ahmed M. Sharif Janahi, Fatma Ben Abid, Adila Shaukat Ali Kashaf, Gulab Sher, Vinod Kumar Gupta, Godwin J. Wilson, Junais Kadalayi, Sanjay H. Doiphode
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bbee38a4063f4217a1787967814a8452
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Sumario:Abstract The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to 2018 were revived and identified by Vitek, and susceptibility on the basis of the E test was retrieved from the patient’s files. The revived isolates were subjected to multilocus sequence typing. The most common serogroup (19) of N. meningitidis was W135, of which 12 were isolated from blood and CSF. ST-11 was the most predominant ST clonal complex causing N. meningitidis cases (61.53%). Clonal complex ST-41/44 was the second most observed complex (3, 2 of which were related to serogroup B). The most frequent sequence type was 9596 (8 isolates). Determining the molecular pattern of N. meningitidis in Qatar is helpful for understanding the strains circulating in Qatar, and the study of the resistance trend of such strains may be very helpful for empirical treatment of future patients.