Molecular characteristics of Neisseria meningitidis in Qatar

Abstract The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to...

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Autores principales:	Manal Mahmoud Hamed, Fayaz Ahmad Mir, Emad Bashier Ibrahim Elmagboul, Abdullatif Al-Khal, Muna A. Rahman S. Al. Maslamani, Anand Sarwottam Deshmukh, Hamad Eid Al-Romaihi, Mohd. Ahmed M. Sharif Janahi, Fatma Ben Abid, Adila Shaukat Ali Kashaf, Gulab Sher, Vinod Kumar Gupta, Godwin J. Wilson, Junais Kadalayi, Sanjay H. Doiphode
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bbee38a4063f4217a1787967814a8452
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spelling	oai:doaj.org-article:bbee38a4063f4217a1787967814a84522021-12-02T11:35:58ZMolecular characteristics of Neisseria meningitidis in Qatar10.1038/s41598-021-84262-12045-2322https://doaj.org/article/bbee38a4063f4217a1787967814a84522021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84262-1https://doaj.org/toc/2045-2322Abstract The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to 2018 were revived and identified by Vitek, and susceptibility on the basis of the E test was retrieved from the patient’s files. The revived isolates were subjected to multilocus sequence typing. The most common serogroup (19) of N. meningitidis was W135, of which 12 were isolated from blood and CSF. ST-11 was the most predominant ST clonal complex causing N. meningitidis cases (61.53%). Clonal complex ST-41/44 was the second most observed complex (3, 2 of which were related to serogroup B). The most frequent sequence type was 9596 (8 isolates). Determining the molecular pattern of N. meningitidis in Qatar is helpful for understanding the strains circulating in Qatar, and the study of the resistance trend of such strains may be very helpful for empirical treatment of future patients.Manal Mahmoud HamedFayaz Ahmad MirEmad Bashier Ibrahim ElmagboulAbdullatif Al-KhalMuna A. Rahman S. Al. MaslamaniAnand Sarwottam DeshmukhHamad Eid Al-RomaihiMohd. Ahmed M. Sharif JanahiFatma Ben AbidAdila Shaukat Ali KashafGulab SherVinod Kumar GuptaGodwin J. WilsonJunais KadalayiSanjay H. DoiphodeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Manal Mahmoud Hamed Fayaz Ahmad Mir Emad Bashier Ibrahim Elmagboul Abdullatif Al-Khal Muna A. Rahman S. Al. Maslamani Anand Sarwottam Deshmukh Hamad Eid Al-Romaihi Mohd. Ahmed M. Sharif Janahi Fatma Ben Abid Adila Shaukat Ali Kashaf Gulab Sher Vinod Kumar Gupta Godwin J. Wilson Junais Kadalayi Sanjay H. Doiphode Molecular characteristics of Neisseria meningitidis in Qatar
description	Abstract The aim of the current study is to review the molecular characteristics of Neisseria meningitidis (N. meningitidis) in Hamad Medical Corporation, which is the provider of secondary and tertiary care in the state of Qatar. A total of 39 isolates of N. meningitidis from the period of 2013 to 2018 were revived and identified by Vitek, and susceptibility on the basis of the E test was retrieved from the patient’s files. The revived isolates were subjected to multilocus sequence typing. The most common serogroup (19) of N. meningitidis was W135, of which 12 were isolated from blood and CSF. ST-11 was the most predominant ST clonal complex causing N. meningitidis cases (61.53%). Clonal complex ST-41/44 was the second most observed complex (3, 2 of which were related to serogroup B). The most frequent sequence type was 9596 (8 isolates). Determining the molecular pattern of N. meningitidis in Qatar is helpful for understanding the strains circulating in Qatar, and the study of the resistance trend of such strains may be very helpful for empirical treatment of future patients.
format	article
author	Manal Mahmoud Hamed Fayaz Ahmad Mir Emad Bashier Ibrahim Elmagboul Abdullatif Al-Khal Muna A. Rahman S. Al. Maslamani Anand Sarwottam Deshmukh Hamad Eid Al-Romaihi Mohd. Ahmed M. Sharif Janahi Fatma Ben Abid Adila Shaukat Ali Kashaf Gulab Sher Vinod Kumar Gupta Godwin J. Wilson Junais Kadalayi Sanjay H. Doiphode
author_facet	Manal Mahmoud Hamed Fayaz Ahmad Mir Emad Bashier Ibrahim Elmagboul Abdullatif Al-Khal Muna A. Rahman S. Al. Maslamani Anand Sarwottam Deshmukh Hamad Eid Al-Romaihi Mohd. Ahmed M. Sharif Janahi Fatma Ben Abid Adila Shaukat Ali Kashaf Gulab Sher Vinod Kumar Gupta Godwin J. Wilson Junais Kadalayi Sanjay H. Doiphode
author_sort	Manal Mahmoud Hamed
title	Molecular characteristics of Neisseria meningitidis in Qatar
title_short	Molecular characteristics of Neisseria meningitidis in Qatar
title_full	Molecular characteristics of Neisseria meningitidis in Qatar
title_fullStr	Molecular characteristics of Neisseria meningitidis in Qatar
title_full_unstemmed	Molecular characteristics of Neisseria meningitidis in Qatar
title_sort	molecular characteristics of neisseria meningitidis in qatar
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bbee38a4063f4217a1787967814a8452
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Molecular characteristics of Neisseria meningitidis in Qatar

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