Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence. Here, the authors report biocompatible gold nanorods and thermal-sensitive hydrogel to promote narrowing of blood vessels and show this to reduce tumour growth and metasta...

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Autores principales: Kun Zhang, Yan Fang, Yaping He, Haohao Yin, Xin Guan, Yinying Pu, Bangguo Zhou, Wenwen Yue, Weiwei Ren, Dou Du, Hongyan Li, Chang Liu, Liping Sun, Yu Chen, Huixiong Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/bbff732ee41f4a29aee08021301ba0fb
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Sumario:The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence. Here, the authors report biocompatible gold nanorods and thermal-sensitive hydrogel to promote narrowing of blood vessels and show this to reduce tumour growth and metastasis.