Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence. Here, the authors report biocompatible gold nanorods and thermal-sensitive hydrogel to promote narrowing of blood vessels and show this to reduce tumour growth and metasta...

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Autores principales: Kun Zhang, Yan Fang, Yaping He, Haohao Yin, Xin Guan, Yinying Pu, Bangguo Zhou, Wenwen Yue, Weiwei Ren, Dou Du, Hongyan Li, Chang Liu, Liping Sun, Yu Chen, Huixiong Xu
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/bbff732ee41f4a29aee08021301ba0fb
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spelling oai:doaj.org-article:bbff732ee41f4a29aee08021301ba0fb2021-12-02T15:35:58ZExtravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence10.1038/s41467-019-13115-32041-1723https://doaj.org/article/bbff732ee41f4a29aee08021301ba0fb2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13115-3https://doaj.org/toc/2041-1723The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence. Here, the authors report biocompatible gold nanorods and thermal-sensitive hydrogel to promote narrowing of blood vessels and show this to reduce tumour growth and metastasis.Kun ZhangYan FangYaping HeHaohao YinXin GuanYinying PuBangguo ZhouWenwen YueWeiwei RenDou DuHongyan LiChang LiuLiping SunYu ChenHuixiong XuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kun Zhang
Yan Fang
Yaping He
Haohao Yin
Xin Guan
Yinying Pu
Bangguo Zhou
Wenwen Yue
Weiwei Ren
Dou Du
Hongyan Li
Chang Liu
Liping Sun
Yu Chen
Huixiong Xu
Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
description The efficacy of tumour starvation therapy is limited by lack of persistent tumour suppression, tumour metastasis and recurrence. Here, the authors report biocompatible gold nanorods and thermal-sensitive hydrogel to promote narrowing of blood vessels and show this to reduce tumour growth and metastasis.
format article
author Kun Zhang
Yan Fang
Yaping He
Haohao Yin
Xin Guan
Yinying Pu
Bangguo Zhou
Wenwen Yue
Weiwei Ren
Dou Du
Hongyan Li
Chang Liu
Liping Sun
Yu Chen
Huixiong Xu
author_facet Kun Zhang
Yan Fang
Yaping He
Haohao Yin
Xin Guan
Yinying Pu
Bangguo Zhou
Wenwen Yue
Weiwei Ren
Dou Du
Hongyan Li
Chang Liu
Liping Sun
Yu Chen
Huixiong Xu
author_sort Kun Zhang
title Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
title_short Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
title_full Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
title_fullStr Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
title_full_unstemmed Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
title_sort extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/bbff732ee41f4a29aee08021301ba0fb
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