Intracellular localization of nanoparticle dimers by chirality reversal

The ability to spectroscopically pinpoint whether nanoparticles are located inside or outside of cells represents an overarching need in biology and medicine. Here, the authors show that the chirality of DNA-bridged particle dimers reverses when they cross the cell membrane, providing a real-time ch...

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Autores principales:	Maozhong Sun, Liguang Xu, Joong Hwan Bahng, Hua Kuang, Silas Alben, Nicholas A. Kotov, Chuanlai Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bc0f87cac8f04c079df75851fac85d5d
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spelling	oai:doaj.org-article:bc0f87cac8f04c079df75851fac85d5d2021-12-02T15:38:57ZIntracellular localization of nanoparticle dimers by chirality reversal10.1038/s41467-017-01337-22041-1723https://doaj.org/article/bc0f87cac8f04c079df75851fac85d5d2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01337-2https://doaj.org/toc/2041-1723The ability to spectroscopically pinpoint whether nanoparticles are located inside or outside of cells represents an overarching need in biology and medicine. Here, the authors show that the chirality of DNA-bridged particle dimers reverses when they cross the cell membrane, providing a real-time chiroptical signature of their intra- or extracellular location.Maozhong SunLiguang XuJoong Hwan BahngHua KuangSilas AlbenNicholas A. KotovChuanlai XuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maozhong Sun Liguang Xu Joong Hwan Bahng Hua Kuang Silas Alben Nicholas A. Kotov Chuanlai Xu Intracellular localization of nanoparticle dimers by chirality reversal
description	The ability to spectroscopically pinpoint whether nanoparticles are located inside or outside of cells represents an overarching need in biology and medicine. Here, the authors show that the chirality of DNA-bridged particle dimers reverses when they cross the cell membrane, providing a real-time chiroptical signature of their intra- or extracellular location.
format	article
author	Maozhong Sun Liguang Xu Joong Hwan Bahng Hua Kuang Silas Alben Nicholas A. Kotov Chuanlai Xu
author_facet	Maozhong Sun Liguang Xu Joong Hwan Bahng Hua Kuang Silas Alben Nicholas A. Kotov Chuanlai Xu
author_sort	Maozhong Sun
title	Intracellular localization of nanoparticle dimers by chirality reversal
title_short	Intracellular localization of nanoparticle dimers by chirality reversal
title_full	Intracellular localization of nanoparticle dimers by chirality reversal
title_fullStr	Intracellular localization of nanoparticle dimers by chirality reversal
title_full_unstemmed	Intracellular localization of nanoparticle dimers by chirality reversal
title_sort	intracellular localization of nanoparticle dimers by chirality reversal
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bc0f87cac8f04c079df75851fac85d5d
work_keys_str_mv	AT maozhongsun intracellularlocalizationofnanoparticledimersbychiralityreversal AT liguangxu intracellularlocalizationofnanoparticledimersbychiralityreversal AT joonghwanbahng intracellularlocalizationofnanoparticledimersbychiralityreversal AT huakuang intracellularlocalizationofnanoparticledimersbychiralityreversal AT silasalben intracellularlocalizationofnanoparticledimersbychiralityreversal AT nicholasakotov intracellularlocalizationofnanoparticledimersbychiralityreversal AT chuanlaixu intracellularlocalizationofnanoparticledimersbychiralityreversal
_version_	1718386012552429568

Intracellular localization of nanoparticle dimers by chirality reversal

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