Unconventional conservation reveals structure-function relationships in the synaptonemal complex
Functional requirements constrain protein evolution, commonly manifesting in a conserved amino acid sequence. Here, we extend this idea to secondary structural features by tracking their conservation in essential meiotic proteins with highly diverged sequences. The synaptonemal complex (SC) is a ~10...
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Main Authors: | Lisa E Kursel, Henry D Cope, Ofer Rog |
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Format: | article |
Language: | EN |
Published: |
eLife Sciences Publications Ltd
2021
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Online Access: | https://doaj.org/article/bc16d92a8a5a42d0b4692e96904a7b5b |
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