Emergence of <italic toggle="yes">mcr-9.1</italic> in Extended-Spectrum-β-Lactamase-Producing Clinical <italic toggle="yes">Enterobacteriaceae</italic> in Pretoria, South Africa: Global Evolutionary Phylogenomics, Resistome, and Mobilome

Emergence of <italic toggle="yes">mcr-9.1</italic> in Extended-Spectrum-β-Lactamase-Producing Clinical <italic toggle="yes">Enterobacteriaceae</italic> in Pretoria, South Africa: Global Evolutionary Phylogenomics, Resistome, and Mobilome

ABSTRACT Extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae are critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr genes mediating resistance to colistin in Enterobacteriaceae, clinicians are now left with few therapeutic options. Eleven cl...

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Bibliographic Details
Main Authors: John Osei Sekyere, Nontuthuko E. Maningi, Lesedi Modipane, Nontombi Marylucy Mbelle
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
ESBLs
Enterobacteriaceae
mcr-9.1
South Africa
critical pathogens
colistin resistance
Microbiology
QR1-502
Online Access:https://doaj.org/article/bc30c5954be84a7b9ec03f15f70fa197
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