Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen

Abstract Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D4 receptor (D4R), which is expressed in the caudate putamen (CPu), mainly counteracts mor...

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Autores principales: Alejandra Valderrama-Carvajal, Haritz Irizar, Belén Gago, Haritz Jiménez-Urbieta, Kjell Fuxe, María C. Rodríguez-Oroz, David Otaegui, Alicia Rivera
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bc34cc152564482a90c65b2b3ba4e09a
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