The autophagy protein ATG9A enables lipid mobilization from lipid droplets

ATG9A is transmembrane autophagic machinery protein that delivers phospholipids to expanding autophagosomes. Mailler et al. show that ATG9A is required to mobilize lipids from lipid droplets for autophagosome expansion as well as mitochondrial fatty acid import and β-oxidation.

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Autores principales:	Elodie Mailler, Carlos M. Guardia, Xiaofei Bai, Michal Jarnik, Chad D. Williamson, Yan Li, Nunziata Maio, Andy Golden, Juan S. Bonifacino
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bc3b482686c54ef6a34fb727e681922d
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spelling	oai:doaj.org-article:bc3b482686c54ef6a34fb727e681922d2021-11-21T12:35:43ZThe autophagy protein ATG9A enables lipid mobilization from lipid droplets10.1038/s41467-021-26999-x2041-1723https://doaj.org/article/bc3b482686c54ef6a34fb727e681922d2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26999-xhttps://doaj.org/toc/2041-1723ATG9A is transmembrane autophagic machinery protein that delivers phospholipids to expanding autophagosomes. Mailler et al. show that ATG9A is required to mobilize lipids from lipid droplets for autophagosome expansion as well as mitochondrial fatty acid import and β-oxidation.Elodie MaillerCarlos M. GuardiaXiaofei BaiMichal JarnikChad D. WilliamsonYan LiNunziata MaioAndy GoldenJuan S. BonifacinoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elodie Mailler Carlos M. Guardia Xiaofei Bai Michal Jarnik Chad D. Williamson Yan Li Nunziata Maio Andy Golden Juan S. Bonifacino The autophagy protein ATG9A enables lipid mobilization from lipid droplets
description	ATG9A is transmembrane autophagic machinery protein that delivers phospholipids to expanding autophagosomes. Mailler et al. show that ATG9A is required to mobilize lipids from lipid droplets for autophagosome expansion as well as mitochondrial fatty acid import and β-oxidation.
format	article
author	Elodie Mailler Carlos M. Guardia Xiaofei Bai Michal Jarnik Chad D. Williamson Yan Li Nunziata Maio Andy Golden Juan S. Bonifacino
author_facet	Elodie Mailler Carlos M. Guardia Xiaofei Bai Michal Jarnik Chad D. Williamson Yan Li Nunziata Maio Andy Golden Juan S. Bonifacino
author_sort	Elodie Mailler
title	The autophagy protein ATG9A enables lipid mobilization from lipid droplets
title_short	The autophagy protein ATG9A enables lipid mobilization from lipid droplets
title_full	The autophagy protein ATG9A enables lipid mobilization from lipid droplets
title_fullStr	The autophagy protein ATG9A enables lipid mobilization from lipid droplets
title_full_unstemmed	The autophagy protein ATG9A enables lipid mobilization from lipid droplets
title_sort	autophagy protein atg9a enables lipid mobilization from lipid droplets
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bc3b482686c54ef6a34fb727e681922d
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The autophagy protein ATG9A enables lipid mobilization from lipid droplets

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