Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus

Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of&...

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Autores principales: Nhiem Tran, Aparna Mir, Dhriti Mallik, et al
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Publicado: Dove Medical Press 2010
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spelling oai:doaj.org-article:bc3c2abc52ef4133873d263318ef4a982021-12-02T04:19:56ZBactericidal effect of iron oxide nanoparticles on Staphylococcus aureus1176-91141178-2013https://doaj.org/article/bc3c2abc52ef4133873d263318ef4a982010-04-01T00:00:00Zhttp://www.dovepress.com/bactericidal-effect-of-iron-oxide-nanoparticles-on-staphylococcus-aure-a4247https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of  Engineering and Department of Orthopedics, Brown University, Providence, Rhode Island, USAAbstract: In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at thehighest concentration (3 mg/mL) at all time points.Keywords: nanotechnology, drug delivery, bactericide, magnetic nanoparticles Nhiem TranAparna MirDhriti Malliket alDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2010, Iss default, Pp 277-283 (2010)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Nhiem Tran
Aparna Mir
Dhriti Mallik
et al
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
description Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of  Engineering and Department of Orthopedics, Brown University, Providence, Rhode Island, USAAbstract: In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at thehighest concentration (3 mg/mL) at all time points.Keywords: nanotechnology, drug delivery, bactericide, magnetic nanoparticles
format article
author Nhiem Tran
Aparna Mir
Dhriti Mallik
et al
author_facet Nhiem Tran
Aparna Mir
Dhriti Mallik
et al
author_sort Nhiem Tran
title Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
title_short Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
title_full Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
title_fullStr Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
title_full_unstemmed Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
title_sort bactericidal effect of iron oxide nanoparticles on staphylococcus aureus
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/bc3c2abc52ef4133873d263318ef4a98
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AT aparnamir bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus
AT dhritimallik bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus
AT etal bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus
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