Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus
Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of&...
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Dove Medical Press
2010
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oai:doaj.org-article:bc3c2abc52ef4133873d263318ef4a982021-12-02T04:19:56ZBactericidal effect of iron oxide nanoparticles on Staphylococcus aureus1176-91141178-2013https://doaj.org/article/bc3c2abc52ef4133873d263318ef4a982010-04-01T00:00:00Zhttp://www.dovepress.com/bactericidal-effect-of-iron-oxide-nanoparticles-on-staphylococcus-aure-a4247https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of  Engineering and Department of Orthopedics, Brown University, Providence, Rhode Island, USAAbstract: In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at thehighest concentration (3 mg/mL) at all time points.Keywords: nanotechnology, drug delivery, bactericide, magnetic nanoparticles Nhiem TranAparna MirDhriti Malliket alDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2010, Iss default, Pp 277-283 (2010) |
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Medicine (General) R5-920 Nhiem Tran Aparna Mir Dhriti Mallik et al Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
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Nhiem Tran1, Aparna Mir2, Dhriti Mallik2, Arvind Sinha2, Suprabha Nayar2, Thomas J Webster31Department of Physics, Brown University, Providence, Rhode Island, USA; 2Department of Materials Science and Technology, National Metallurgical Laboratory, Burmamnines 831007, Jamshedpur, India; 3Division of  Engineering and Department of Orthopedics, Brown University, Providence, Rhode Island, USAAbstract: In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at thehighest concentration (3 mg/mL) at all time points.Keywords: nanotechnology, drug delivery, bactericide, magnetic nanoparticles |
format |
article |
author |
Nhiem Tran Aparna Mir Dhriti Mallik et al |
author_facet |
Nhiem Tran Aparna Mir Dhriti Mallik et al |
author_sort |
Nhiem Tran |
title |
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
title_short |
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
title_full |
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
title_fullStr |
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
title_full_unstemmed |
Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus |
title_sort |
bactericidal effect of iron oxide nanoparticles on staphylococcus aureus |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/bc3c2abc52ef4133873d263318ef4a98 |
work_keys_str_mv |
AT nhiemtran bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus AT aparnamir bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus AT dhritimallik bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus AT etal bactericidaleffectofironoxidenanoparticlesonstaphylococcusaureus |
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