A single-cell transcriptomic landscape of primate arterial aging

A single-cell transcriptomic landscape of primate arterial aging

Arterial degeneration, closely associated with cardiovascular diseases, is driven by aging-related vascular cell-specific transcriptomics changes. This study provides a single-cell transcriptomic atlas for senile aortic and coronary arteries and underscores FOXO3A-based the transcriptional network i...

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Autores principales: Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song, Jingyi Li, Jinghui Lei, Huize Pan, Si Wang, Xibo Ma, Shuai Ma, Hongyu Li, Fei Sun, Haifeng Wan, Wei Li, Piu Chan, Qi Zhou, Guang-Hui Liu, Fuchou Tang, Jing Qu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bc45b19f863e4ff7a93ddeb5f74f6aad
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spelling oai:doaj.org-article:bc45b19f863e4ff7a93ddeb5f74f6aad2021-12-02T14:41:15ZA single-cell transcriptomic landscape of primate arterial aging10.1038/s41467-020-15997-02041-1723https://doaj.org/article/bc45b19f863e4ff7a93ddeb5f74f6aad2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15997-0https://doaj.org/toc/2041-1723Arterial degeneration, closely associated with cardiovascular diseases, is driven by aging-related vascular cell-specific transcriptomics changes. This study provides a single-cell transcriptomic atlas for senile aortic and coronary arteries and underscores FOXO3A-based the transcriptional network in vasoprotection during aging.Weiqi ZhangShu ZhangPengze YanJie RenMoshi SongJingyi LiJinghui LeiHuize PanSi WangXibo MaShuai MaHongyu LiFei SunHaifeng WanWei LiPiu ChanQi ZhouGuang-Hui LiuFuchou TangJing QuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Weiqi Zhang
Shu Zhang
Pengze Yan
Jie Ren
Moshi Song
Jingyi Li
Jinghui Lei
Huize Pan
Si Wang
Xibo Ma
Shuai Ma
Hongyu Li
Fei Sun
Haifeng Wan
Wei Li
Piu Chan
Qi Zhou
Guang-Hui Liu
Fuchou Tang
Jing Qu
A single-cell transcriptomic landscape of primate arterial aging
description Arterial degeneration, closely associated with cardiovascular diseases, is driven by aging-related vascular cell-specific transcriptomics changes. This study provides a single-cell transcriptomic atlas for senile aortic and coronary arteries and underscores FOXO3A-based the transcriptional network in vasoprotection during aging.
format article
author Weiqi Zhang
Shu Zhang
Pengze Yan
Jie Ren
Moshi Song
Jingyi Li
Jinghui Lei
Huize Pan
Si Wang
Xibo Ma
Shuai Ma
Hongyu Li
Fei Sun
Haifeng Wan
Wei Li
Piu Chan
Qi Zhou
Guang-Hui Liu
Fuchou Tang
Jing Qu
author_facet Weiqi Zhang
Shu Zhang
Pengze Yan
Jie Ren
Moshi Song
Jingyi Li
Jinghui Lei
Huize Pan
Si Wang
Xibo Ma
Shuai Ma
Hongyu Li
Fei Sun
Haifeng Wan
Wei Li
Piu Chan
Qi Zhou
Guang-Hui Liu
Fuchou Tang
Jing Qu
author_sort Weiqi Zhang
title A single-cell transcriptomic landscape of primate arterial aging
title_short A single-cell transcriptomic landscape of primate arterial aging
title_full A single-cell transcriptomic landscape of primate arterial aging
title_fullStr A single-cell transcriptomic landscape of primate arterial aging
title_full_unstemmed A single-cell transcriptomic landscape of primate arterial aging
title_sort single-cell transcriptomic landscape of primate arterial aging
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/bc45b19f863e4ff7a93ddeb5f74f6aad
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