Nanotoxicology and nanoparticle safety in biomedical designs

Jafar Ai1, Esmaeil Biazar2, Mostafa Jafarpour3, Mohamad Montazeri4, Ali Majdi5, Saba Aminifard5, Mandana Zafari5, Hanie Akbari R6, Hadi Rad Gh71Department of Tissue Engineering, Faculty of Advanced Technologies, Tehran University of Medical Sciences, Tehran; 2Department of Chemistry, Islamic Azad Un...

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Autores principales:	Ai J, Biazar E, Jafarpour M, Montazeri M, Majdi A, Aminifard S, Zafari M, Akbari HR, Rad HG
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/bc5e5ceb9a694726bb5940d770aa588d
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spelling	oai:doaj.org-article:bc5e5ceb9a694726bb5940d770aa588d2021-12-02T02:51:10ZNanotoxicology and nanoparticle safety in biomedical designs1176-91141178-2013https://doaj.org/article/bc5e5ceb9a694726bb5940d770aa588d2011-05-01T00:00:00Zhttp://www.dovepress.com/nanotoxicology-and-nanoparticle-safety-in-biomedical-designs-a7564https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Jafar Ai1, Esmaeil Biazar2, Mostafa Jafarpour3, Mohamad Montazeri4, Ali Majdi5, Saba Aminifard5, Mandana Zafari5, Hanie Akbari R6, Hadi Rad Gh71Department of Tissue Engineering, Faculty of Advanced Technologies, Tehran University of Medical Sciences, Tehran; 2Department of Chemistry, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran; 3Department of Microbiology, Faculty of Science, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran; 4Faculty of Medical Sciences, Babol University of Medical Sciences; 5Young Researchers Club &ndash; Islamic Azad University, Tonekabon Branch, Mazandaran; 6Faculty of Medical Sciences, Islamic Azad University &ndash; North branch, Tehran; 7Faculty of Medical Sciences, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran, IranAbstract: Nanotechnology has wide applications in many fields, especially in the biological sciences and medicine. Nanomaterials are applied as coating materials or in treatment and diagnosis. Nanoparticles such as titania, zirconia, silver, diamonds, iron oxides, carbon nanotubes, and biodegradable polymers have been studied in diagnosis and treatment. Many of these nanoparticles may have toxic effects on cells. Many factors such as size, inherent properties, and surface chemistry may cause nanoparticle toxicity. There are methods for improving the performance and reducing toxicity of nanoparticles in medical design, such as biocompatible coating materials or biodegradable/biocompatible nanoparticles. Most metal oxide nanoparticles show toxic effects, but no toxic effects have been observed with biocompatible coatings. Biodegradable nanoparticles are also used in the efficient design of medical materials, which will be reviewed in this article.Keywords: nanotechnology, nanotoxicology, nanomaterials, nanobiomaterialsAi JBiazar EJafarpour MMontazeri MMajdi AAminifard SZafari MAkbari HRRad HGDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2011, Iss default, Pp 1117-1127 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Ai J Biazar E Jafarpour M Montazeri M Majdi A Aminifard S Zafari M Akbari HR Rad HG Nanotoxicology and nanoparticle safety in biomedical designs
description	Jafar Ai1, Esmaeil Biazar2, Mostafa Jafarpour3, Mohamad Montazeri4, Ali Majdi5, Saba Aminifard5, Mandana Zafari5, Hanie Akbari R6, Hadi Rad Gh71Department of Tissue Engineering, Faculty of Advanced Technologies, Tehran University of Medical Sciences, Tehran; 2Department of Chemistry, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran; 3Department of Microbiology, Faculty of Science, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran; 4Faculty of Medical Sciences, Babol University of Medical Sciences; 5Young Researchers Club &ndash; Islamic Azad University, Tonekabon Branch, Mazandaran; 6Faculty of Medical Sciences, Islamic Azad University &ndash; North branch, Tehran; 7Faculty of Medical Sciences, Islamic Azad University &ndash; Tonekabon Branch, Mazandaran, IranAbstract: Nanotechnology has wide applications in many fields, especially in the biological sciences and medicine. Nanomaterials are applied as coating materials or in treatment and diagnosis. Nanoparticles such as titania, zirconia, silver, diamonds, iron oxides, carbon nanotubes, and biodegradable polymers have been studied in diagnosis and treatment. Many of these nanoparticles may have toxic effects on cells. Many factors such as size, inherent properties, and surface chemistry may cause nanoparticle toxicity. There are methods for improving the performance and reducing toxicity of nanoparticles in medical design, such as biocompatible coating materials or biodegradable/biocompatible nanoparticles. Most metal oxide nanoparticles show toxic effects, but no toxic effects have been observed with biocompatible coatings. Biodegradable nanoparticles are also used in the efficient design of medical materials, which will be reviewed in this article.Keywords: nanotechnology, nanotoxicology, nanomaterials, nanobiomaterials
format	article
author	Ai J Biazar E Jafarpour M Montazeri M Majdi A Aminifard S Zafari M Akbari HR Rad HG
author_facet	Ai J Biazar E Jafarpour M Montazeri M Majdi A Aminifard S Zafari M Akbari HR Rad HG
author_sort	Ai J
title	Nanotoxicology and nanoparticle safety in biomedical designs
title_short	Nanotoxicology and nanoparticle safety in biomedical designs
title_full	Nanotoxicology and nanoparticle safety in biomedical designs
title_fullStr	Nanotoxicology and nanoparticle safety in biomedical designs
title_full_unstemmed	Nanotoxicology and nanoparticle safety in biomedical designs
title_sort	nanotoxicology and nanoparticle safety in biomedical designs
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/bc5e5ceb9a694726bb5940d770aa588d
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Nanotoxicology and nanoparticle safety in biomedical designs

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