Olfactory dysfunction in Alzheimer’s disease

Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfun...

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Autores principales: Zou YM, Lu D, Liu LP, Zhang HH, Zhou YY
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/bc613c1080a748a8b78f022a1bb91a4c
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spelling oai:doaj.org-article:bc613c1080a748a8b78f022a1bb91a4c2021-12-02T02:44:40ZOlfactory dysfunction in Alzheimer’s disease1178-2021https://doaj.org/article/bc613c1080a748a8b78f022a1bb91a4c2016-04-01T00:00:00Zhttps://www.dovepress.com/olfactory-dysfunction-in-alzheimerrsquos-disease-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction, which is a potential clinical marker for AD severity and progression. However, many questions remain unanswered. This article reviews relevant research on olfactory dysfunction in AD and evaluates the predictive value of olfactory dysfunction for the epidemiological, pathophysiological, and clinical features of AD, as well as for the conversion of cognitive impairment to AD. We summarize problems of existing studies and provide a useful reference for further studies in AD olfactory dysfunction and for clinical applications of olfactory testing. Keywords: olfactory dysfunction, Alzheimer’s disease, olfactory testing, progressZou YMLu DLiu LPZhang HHZhou YYDove Medical Pressarticleolfactory dysfunctionAlzheimer’s diseaseolfactory testingprogressNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 869-875 (2016)
institution DOAJ
collection DOAJ
language EN
topic olfactory dysfunction
Alzheimer’s disease
olfactory testing
progress
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle olfactory dysfunction
Alzheimer’s disease
olfactory testing
progress
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Zou YM
Lu D
Liu LP
Zhang HH
Zhou YY
Olfactory dysfunction in Alzheimer’s disease
description Yong-ming Zou, Da Lu, Li-ping Liu, Hui-hong Zhang, Yu-ying Zhou Department of Neurology, Tianjin Huanhu Hospital, Tianjin, People’s Republic of China Abstract: Alzheimer’s disease (AD) is a common neurodegenerative disorder with the earliest clinical symptom of olfactory dysfunction, which is a potential clinical marker for AD severity and progression. However, many questions remain unanswered. This article reviews relevant research on olfactory dysfunction in AD and evaluates the predictive value of olfactory dysfunction for the epidemiological, pathophysiological, and clinical features of AD, as well as for the conversion of cognitive impairment to AD. We summarize problems of existing studies and provide a useful reference for further studies in AD olfactory dysfunction and for clinical applications of olfactory testing. Keywords: olfactory dysfunction, Alzheimer’s disease, olfactory testing, progress
format article
author Zou YM
Lu D
Liu LP
Zhang HH
Zhou YY
author_facet Zou YM
Lu D
Liu LP
Zhang HH
Zhou YY
author_sort Zou YM
title Olfactory dysfunction in Alzheimer’s disease
title_short Olfactory dysfunction in Alzheimer’s disease
title_full Olfactory dysfunction in Alzheimer’s disease
title_fullStr Olfactory dysfunction in Alzheimer’s disease
title_full_unstemmed Olfactory dysfunction in Alzheimer’s disease
title_sort olfactory dysfunction in alzheimer’s disease
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/bc613c1080a748a8b78f022a1bb91a4c
work_keys_str_mv AT zouym olfactorydysfunctioninalzheimerrsquosdisease
AT lud olfactorydysfunctioninalzheimerrsquosdisease
AT liulp olfactorydysfunctioninalzheimerrsquosdisease
AT zhanghh olfactorydysfunctioninalzheimerrsquosdisease
AT zhouyy olfactorydysfunctioninalzheimerrsquosdisease
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