Cellular forces and matrix assembly coordinate fibrous tissue repair

Planar in vitromodels for wound closure stress the role of lamellipodial protrusions and purse-string contraction. Here the authors develop a 3D biomimetic model for tissue repair and show a mode of stromal closure that relies on whole tissue deformations, cell migration and matrix deposition.

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Autores principales:	Mahmut Selman Sakar, Jeroen Eyckmans, Roel Pieters, Daniel Eberli, Bradley J. Nelson, Christopher S. Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bc6809c44db74a4f8e56024976f8197c
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spelling	oai:doaj.org-article:bc6809c44db74a4f8e56024976f8197c2021-12-02T14:39:51ZCellular forces and matrix assembly coordinate fibrous tissue repair10.1038/ncomms110362041-1723https://doaj.org/article/bc6809c44db74a4f8e56024976f8197c2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11036https://doaj.org/toc/2041-1723Planar in vitromodels for wound closure stress the role of lamellipodial protrusions and purse-string contraction. Here the authors develop a 3D biomimetic model for tissue repair and show a mode of stromal closure that relies on whole tissue deformations, cell migration and matrix deposition.Mahmut Selman SakarJeroen EyckmansRoel PietersDaniel EberliBradley J. NelsonChristopher S. ChenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mahmut Selman Sakar Jeroen Eyckmans Roel Pieters Daniel Eberli Bradley J. Nelson Christopher S. Chen Cellular forces and matrix assembly coordinate fibrous tissue repair
description	Planar in vitromodels for wound closure stress the role of lamellipodial protrusions and purse-string contraction. Here the authors develop a 3D biomimetic model for tissue repair and show a mode of stromal closure that relies on whole tissue deformations, cell migration and matrix deposition.
format	article
author	Mahmut Selman Sakar Jeroen Eyckmans Roel Pieters Daniel Eberli Bradley J. Nelson Christopher S. Chen
author_facet	Mahmut Selman Sakar Jeroen Eyckmans Roel Pieters Daniel Eberli Bradley J. Nelson Christopher S. Chen
author_sort	Mahmut Selman Sakar
title	Cellular forces and matrix assembly coordinate fibrous tissue repair
title_short	Cellular forces and matrix assembly coordinate fibrous tissue repair
title_full	Cellular forces and matrix assembly coordinate fibrous tissue repair
title_fullStr	Cellular forces and matrix assembly coordinate fibrous tissue repair
title_full_unstemmed	Cellular forces and matrix assembly coordinate fibrous tissue repair
title_sort	cellular forces and matrix assembly coordinate fibrous tissue repair
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/bc6809c44db74a4f8e56024976f8197c
work_keys_str_mv	AT mahmutselmansakar cellularforcesandmatrixassemblycoordinatefibroustissuerepair AT jeroeneyckmans cellularforcesandmatrixassemblycoordinatefibroustissuerepair AT roelpieters cellularforcesandmatrixassemblycoordinatefibroustissuerepair AT danieleberli cellularforcesandmatrixassemblycoordinatefibroustissuerepair AT bradleyjnelson cellularforcesandmatrixassemblycoordinatefibroustissuerepair AT christopherschen cellularforcesandmatrixassemblycoordinatefibroustissuerepair
_version_	1718390498637381632

Cellular forces and matrix assembly coordinate fibrous tissue repair

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