Reciprocal regulation of TLR2-mediated IFN-β production by SHP2 and Gsk3β
Abstract Toll-like receptor 2 (TLR2) mediates the innate immune response to bacterial lipopeptides and peptidoglycans by stimulating the production of inflammatory cytokines. However, the mechanisms by which TLR2 signaling regulates type I interferon (IFN)-β production are poorly understood. Here, w...
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Autores principales: | Jin Hee Park, Ryeojin Ko, Soo Young Lee |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/bc6829427a2f4100a7a6707e016f9cdf |
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