Reciprocal regulation of TLR2-mediated IFN-β production by SHP2 and Gsk3β

Abstract Toll-like receptor 2 (TLR2) mediates the innate immune response to bacterial lipopeptides and peptidoglycans by stimulating the production of inflammatory cytokines. However, the mechanisms by which TLR2 signaling regulates type I interferon (IFN)-β production are poorly understood. Here, w...

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Bibliographic Details
Main Authors: Jin Hee Park, Ryeojin Ko, Soo Young Lee
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/bc6829427a2f4100a7a6707e016f9cdf
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