Generation of a rod-specific NRL reporter line in human pluripotent stem cells

Generation of a rod-specific NRL reporter line in human pluripotent stem cells

Abstract Reporter lines generated in human pluripotent stem cells can be highly useful for the analysis of specific cell types and lineages in live cultures. We created the first human rod reporter line using CRISPR/Cas9 genome editing to replace one allele of the Neural Retina Leucine zipper (NRL)...

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Autores principales: M. Joseph Phillips, Elizabeth E. Capowski, Andrew Petersen, Alex D. Jansen, Katherine Barlow, Kimberly L. Edwards, David M. Gamm
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bc6bee677a18423c99acf52dbb951ec4
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