Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction

Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatiti...

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Autores principales: Walaa El Arja, Sarah B. Eid, Elias Saikaly, Lynn Ezzeddine, Rayan Daoud, Elias Fiani
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Lenguaje:EN
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
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Acceso en línea:https://doaj.org/article/bc70e73039c74ccbaadf4add814066c0
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spelling oai:doaj.org-article:bc70e73039c74ccbaadf4add814066c02021-11-10T23:54:33ZLaparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction2455-74202455-094910.1055/s-0041-1736448https://doaj.org/article/bc70e73039c74ccbaadf4add814066c02021-11-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1736448https://doaj.org/toc/2455-7420https://doaj.org/toc/2455-0949Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatitis, and many others. A 50-year-old woman with stage IV breast cancer who underwent radioembolization for unresectable hepatic metastasis 6 months ago presented to our hospital with 1 month history of nausea, vomiting, with food intolerance, and weight loss. Esophagogastroduodenoscopy showed large deep duodenal bulbar ulcer along with antral ulcerations and edematous gastropathy. Biopsies revealed typical black, duodenal yttrium-90 sphere, documenting radiation injury. After she was discharged on proton pump inhibitor, the patient came back 1 month later for exacerbation of symptoms; computed tomography scan of the abdomen showed gastric outlet obstruction. Although there is no consensus in treating radiation-induced ulcers, physicians should be aware of this complication in patient who underwent SIRT presenting for abdominal pain.Walaa El ArjaSarah B. EidElias SaikalyLynn EzzeddineRayan DaoudElias FianiThieme Medical and Scientific Publishers Pvt. Ltd.articleduodenal ulcergastric outlet obstructiongastrojejunostomyradioembolizationyttrium-90Orthopedic surgeryRD701-811ENInternational Journal of Recent Surgical and Medical Sciences (2021)
institution DOAJ
collection DOAJ
language EN
topic duodenal ulcer
gastric outlet obstruction
gastrojejunostomy
radioembolization
yttrium-90
Orthopedic surgery
RD701-811
spellingShingle duodenal ulcer
gastric outlet obstruction
gastrojejunostomy
radioembolization
yttrium-90
Orthopedic surgery
RD701-811
Walaa El Arja
Sarah B. Eid
Elias Saikaly
Lynn Ezzeddine
Rayan Daoud
Elias Fiani
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
description Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatitis, and many others. A 50-year-old woman with stage IV breast cancer who underwent radioembolization for unresectable hepatic metastasis 6 months ago presented to our hospital with 1 month history of nausea, vomiting, with food intolerance, and weight loss. Esophagogastroduodenoscopy showed large deep duodenal bulbar ulcer along with antral ulcerations and edematous gastropathy. Biopsies revealed typical black, duodenal yttrium-90 sphere, documenting radiation injury. After she was discharged on proton pump inhibitor, the patient came back 1 month later for exacerbation of symptoms; computed tomography scan of the abdomen showed gastric outlet obstruction. Although there is no consensus in treating radiation-induced ulcers, physicians should be aware of this complication in patient who underwent SIRT presenting for abdominal pain.
format article
author Walaa El Arja
Sarah B. Eid
Elias Saikaly
Lynn Ezzeddine
Rayan Daoud
Elias Fiani
author_facet Walaa El Arja
Sarah B. Eid
Elias Saikaly
Lynn Ezzeddine
Rayan Daoud
Elias Fiani
author_sort Walaa El Arja
title Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
title_short Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
title_full Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
title_fullStr Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
title_full_unstemmed Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
title_sort laparoscopic gastrojejunostomy for the treatment of sirt-induced duodenal ulcer complicated by gastric outlet obstruction
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate 2021
url https://doaj.org/article/bc70e73039c74ccbaadf4add814066c0
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AT sarahbeid laparoscopicgastrojejunostomyforthetreatmentofsirtinducedduodenalulcercomplicatedbygastricoutletobstruction
AT eliassaikaly laparoscopicgastrojejunostomyforthetreatmentofsirtinducedduodenalulcercomplicatedbygastricoutletobstruction
AT lynnezzeddine laparoscopicgastrojejunostomyforthetreatmentofsirtinducedduodenalulcercomplicatedbygastricoutletobstruction
AT rayandaoud laparoscopicgastrojejunostomyforthetreatmentofsirtinducedduodenalulcercomplicatedbygastricoutletobstruction
AT eliasfiani laparoscopicgastrojejunostomyforthetreatmentofsirtinducedduodenalulcercomplicatedbygastricoutletobstruction
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