Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction
Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatiti...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2021
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oai:doaj.org-article:bc70e73039c74ccbaadf4add814066c02021-11-10T23:54:33ZLaparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction2455-74202455-094910.1055/s-0041-1736448https://doaj.org/article/bc70e73039c74ccbaadf4add814066c02021-11-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1736448https://doaj.org/toc/2455-7420https://doaj.org/toc/2455-0949Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatitis, and many others. A 50-year-old woman with stage IV breast cancer who underwent radioembolization for unresectable hepatic metastasis 6 months ago presented to our hospital with 1 month history of nausea, vomiting, with food intolerance, and weight loss. Esophagogastroduodenoscopy showed large deep duodenal bulbar ulcer along with antral ulcerations and edematous gastropathy. Biopsies revealed typical black, duodenal yttrium-90 sphere, documenting radiation injury. After she was discharged on proton pump inhibitor, the patient came back 1 month later for exacerbation of symptoms; computed tomography scan of the abdomen showed gastric outlet obstruction. Although there is no consensus in treating radiation-induced ulcers, physicians should be aware of this complication in patient who underwent SIRT presenting for abdominal pain.Walaa El ArjaSarah B. EidElias SaikalyLynn EzzeddineRayan DaoudElias FianiThieme Medical and Scientific Publishers Pvt. Ltd.articleduodenal ulcergastric outlet obstructiongastrojejunostomyradioembolizationyttrium-90Orthopedic surgeryRD701-811ENInternational Journal of Recent Surgical and Medical Sciences (2021) |
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duodenal ulcer gastric outlet obstruction gastrojejunostomy radioembolization yttrium-90 Orthopedic surgery RD701-811 |
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duodenal ulcer gastric outlet obstruction gastrojejunostomy radioembolization yttrium-90 Orthopedic surgery RD701-811 Walaa El Arja Sarah B. Eid Elias Saikaly Lynn Ezzeddine Rayan Daoud Elias Fiani Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
description |
Selective internal radiation therapy (SIRT) is an emerging therapeutic modality in patients with unresectable hepatocellular carcinoma or liver metastases. However, complications can occur due to migration of radiation microspheres such as gastrointestinal ulcer, cholecystitis, bleeding, pancreatitis, and many others. A 50-year-old woman with stage IV breast cancer who underwent radioembolization for unresectable hepatic metastasis 6 months ago presented to our hospital with 1 month history of nausea, vomiting, with food intolerance, and weight loss. Esophagogastroduodenoscopy showed large deep duodenal bulbar ulcer along with antral ulcerations and edematous gastropathy. Biopsies revealed typical black, duodenal yttrium-90 sphere, documenting radiation injury. After she was discharged on proton pump inhibitor, the patient came back 1 month later for exacerbation of symptoms; computed tomography scan of the abdomen showed gastric outlet obstruction. Although there is no consensus in treating radiation-induced ulcers, physicians should be aware of this complication in patient who underwent SIRT presenting for abdominal pain. |
format |
article |
author |
Walaa El Arja Sarah B. Eid Elias Saikaly Lynn Ezzeddine Rayan Daoud Elias Fiani |
author_facet |
Walaa El Arja Sarah B. Eid Elias Saikaly Lynn Ezzeddine Rayan Daoud Elias Fiani |
author_sort |
Walaa El Arja |
title |
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
title_short |
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
title_full |
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
title_fullStr |
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
title_full_unstemmed |
Laparoscopic Gastrojejunostomy for the Treatment of SIRT-Induced Duodenal Ulcer Complicated by Gastric Outlet Obstruction |
title_sort |
laparoscopic gastrojejunostomy for the treatment of sirt-induced duodenal ulcer complicated by gastric outlet obstruction |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
publishDate |
2021 |
url |
https://doaj.org/article/bc70e73039c74ccbaadf4add814066c0 |
work_keys_str_mv |
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