Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019

Abstract No studies of the efficacy and safety of surgical techniques for the primary closure of giant omphalocele have been performed in Colombia. To determine the mortality rate and factors associated with mortality in neonates with giant omphalocele subjected to the surgical technique of early cl...

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Autores principales:	Alexander Barrios-Sanjuanelo, Cristóbal Abelló-Munarriz, Jaiberth Antonio Cardona-Arias
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bc73d0e1ed534f63bdd805025377c887
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spelling	oai:doaj.org-article:bc73d0e1ed534f63bdd805025377c8872021-12-02T14:01:34ZMortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 201910.1038/s41598-020-78991-y2045-2322https://doaj.org/article/bc73d0e1ed534f63bdd805025377c8872021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78991-yhttps://doaj.org/toc/2045-2322Abstract No studies of the efficacy and safety of surgical techniques for the primary closure of giant omphalocele have been performed in Colombia. To determine the mortality rate and factors associated with mortality in neonates with giant omphalocele subjected to the surgical technique of early closure with a surgical silo described by Abello in Barranquilla, Colombia from 1994 to 2019. Retrospective cohort study of 30 neonates diagnosed with giant omphalocele and subjected to early closure of the defect. Medical history data were collected, information bias was controlled for, and descriptive statistical analysis was performed using Fisher’s exact test and the Mann–Whitney U test in SPSS 25.0. Of the patients in the cohort, 36.7% presented technique-related complications, 56.7% developed sepsis, 23.3% had low birth weight, 26.7% were preterm births, 43.3% had other malformations, 26.7% had congenital heart defects, and 13.3% presented pulmonary hypertension. The mean hospital stay was 26 days. The mortality rate was 16.7%; it was significantly higher among patients with other malformations, congenital heart defects, pentalogy of Cantrell and pulmonary hypertension. The Abello technique for the treatment of giant omphalocele showed a high neonatal survival rate and a low rate of procedure-related complications. The main factors associated with the death of neonatal patients were the presence of other malformations, congenital heart defect, pentalogy of Cantrell and pulmonary hypertension.Alexander Barrios-SanjuaneloCristóbal Abelló-MunarrizJaiberth Antonio Cardona-AriasNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alexander Barrios-Sanjuanelo Cristóbal Abelló-Munarriz Jaiberth Antonio Cardona-Arias Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
description	Abstract No studies of the efficacy and safety of surgical techniques for the primary closure of giant omphalocele have been performed in Colombia. To determine the mortality rate and factors associated with mortality in neonates with giant omphalocele subjected to the surgical technique of early closure with a surgical silo described by Abello in Barranquilla, Colombia from 1994 to 2019. Retrospective cohort study of 30 neonates diagnosed with giant omphalocele and subjected to early closure of the defect. Medical history data were collected, information bias was controlled for, and descriptive statistical analysis was performed using Fisher’s exact test and the Mann–Whitney U test in SPSS 25.0. Of the patients in the cohort, 36.7% presented technique-related complications, 56.7% developed sepsis, 23.3% had low birth weight, 26.7% were preterm births, 43.3% had other malformations, 26.7% had congenital heart defects, and 13.3% presented pulmonary hypertension. The mean hospital stay was 26 days. The mortality rate was 16.7%; it was significantly higher among patients with other malformations, congenital heart defects, pentalogy of Cantrell and pulmonary hypertension. The Abello technique for the treatment of giant omphalocele showed a high neonatal survival rate and a low rate of procedure-related complications. The main factors associated with the death of neonatal patients were the presence of other malformations, congenital heart defect, pentalogy of Cantrell and pulmonary hypertension.
format	article
author	Alexander Barrios-Sanjuanelo Cristóbal Abelló-Munarriz Jaiberth Antonio Cardona-Arias
author_facet	Alexander Barrios-Sanjuanelo Cristóbal Abelló-Munarriz Jaiberth Antonio Cardona-Arias
author_sort	Alexander Barrios-Sanjuanelo
title	Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
title_short	Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
title_full	Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
title_fullStr	Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
title_full_unstemmed	Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019
title_sort	mortality in neonates with giant omphalocele subjected to a surgical technique in barranquilla, colombia from 1994 to 2019
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bc73d0e1ed534f63bdd805025377c887
work_keys_str_mv	AT alexanderbarriossanjuanelo mortalityinneonateswithgiantomphalocelesubjectedtoasurgicaltechniqueinbarranquillacolombiafrom1994to2019 AT cristobalabellomunarriz mortalityinneonateswithgiantomphalocelesubjectedtoasurgicaltechniqueinbarranquillacolombiafrom1994to2019 AT jaiberthantoniocardonaarias mortalityinneonateswithgiantomphalocelesubjectedtoasurgicaltechniqueinbarranquillacolombiafrom1994to2019
_version_	1718392166139559936

Mortality in neonates with giant omphalocele subjected to a surgical technique in Barranquilla, Colombia from 1994 to 2019

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