Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy
X-linked adrenoleukodystophy (X-ALD) is a highly variable, progressive neurodegenerative disorder. In this study, neurofilament light chain protein (NfL) was identified as a potential early distinguishing biomarker.
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Nature Portfolio
2021
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oai:doaj.org-article:bc793312378441c5a3bc5301eb2c17622021-12-02T17:04:30ZNeurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy10.1038/s41467-021-22114-22041-1723https://doaj.org/article/bc793312378441c5a3bc5301eb2c17622021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22114-2https://doaj.org/toc/2041-1723X-linked adrenoleukodystophy (X-ALD) is a highly variable, progressive neurodegenerative disorder. In this study, neurofilament light chain protein (NfL) was identified as a potential early distinguishing biomarker.Isabelle WeinhoferPaulus RommerBettina ZierfussPatrick AltmannMartha FoianiAmanda HeslegraveHenrik ZetterbergAndreas GleissPatricia L. MusolinoYi GongSonja Forss-PetterThomas BergerFlorian EichlerPatrick AubourgWolfgang KöhlerJohannes BergerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Isabelle Weinhofer Paulus Rommer Bettina Zierfuss Patrick Altmann Martha Foiani Amanda Heslegrave Henrik Zetterberg Andreas Gleiss Patricia L. Musolino Yi Gong Sonja Forss-Petter Thomas Berger Florian Eichler Patrick Aubourg Wolfgang Köhler Johannes Berger Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| description |
X-linked adrenoleukodystophy (X-ALD) is a highly variable, progressive neurodegenerative disorder. In this study, neurofilament light chain protein (NfL) was identified as a potential early distinguishing biomarker. |
| format |
article |
| author |
Isabelle Weinhofer Paulus Rommer Bettina Zierfuss Patrick Altmann Martha Foiani Amanda Heslegrave Henrik Zetterberg Andreas Gleiss Patricia L. Musolino Yi Gong Sonja Forss-Petter Thomas Berger Florian Eichler Patrick Aubourg Wolfgang Köhler Johannes Berger |
| author_facet |
Isabelle Weinhofer Paulus Rommer Bettina Zierfuss Patrick Altmann Martha Foiani Amanda Heslegrave Henrik Zetterberg Andreas Gleiss Patricia L. Musolino Yi Gong Sonja Forss-Petter Thomas Berger Florian Eichler Patrick Aubourg Wolfgang Köhler Johannes Berger |
| author_sort |
Isabelle Weinhofer |
| title |
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| title_short |
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| title_full |
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| title_fullStr |
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| title_full_unstemmed |
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy |
| title_sort |
neurofilament light chain as a potential biomarker for monitoring neurodegeneration in x-linked adrenoleukodystrophy |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/bc793312378441c5a3bc5301eb2c1762 |
| work_keys_str_mv |
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