Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits

To understand the biological effects of radiation, it is important to determine how ionizing radiation deposits energy in micrometric targets. The energy deposited in a target located in an irradiated tissue is a function of several factors such as the radiation type and the irradiated volume size....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ianik Plante, Floriane Poignant, Tony Slaba
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	radiation track structure spherical targets energy deposition heavy ions HZE ionizing radiation Science Q
Acceso en línea:	https://doaj.org/article/bc7c3b6500cf4027887248a58326d3e3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:bc7c3b6500cf4027887248a58326d3e3
record_format	dspace
spelling	oai:doaj.org-article:bc7c3b6500cf4027887248a58326d3e32021-11-25T18:10:23ZTrack Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits10.3390/life111111122075-1729https://doaj.org/article/bc7c3b6500cf4027887248a58326d3e32021-10-01T00:00:00Zhttps://www.mdpi.com/2075-1729/11/11/1112https://doaj.org/toc/2075-1729To understand the biological effects of radiation, it is important to determine how ionizing radiation deposits energy in micrometric targets. The energy deposited in a target located in an irradiated tissue is a function of several factors such as the radiation type and the irradiated volume size. We simulated the energy deposited by energetic ions in spherical targets of 1, 2, 4, and 8 µm radii encompassed in irradiated parallelepiped volumes of various sizes using the stochastic radiation track structure code Relativistic Ion Tracks (RITRACKS). Because cells are usually part of a tissue when they are irradiated, electrons originating from radiation tracks in neighboring volumes also contribute to energy deposition in the target. To account for this contribution, we used periodic boundary conditions in the simulations. We found that the single-ion spectra of energy deposition in targets comprises two components: the direct ion hits to the targets, which is identical in all irradiation conditions, and the contribution of hits from electrons from neighboring volumes, which depends on the irradiated volume. We also calculated an analytical expression of the indirect hit contributions using the local effect model, which showed results similar to those obtained with RITRACKS.Ianik PlanteFloriane PoignantTony SlabaMDPI AGarticleradiation track structurespherical targetsenergy depositionheavy ionsHZEionizing radiationScienceQENLife, Vol 11, Iss 1112, p 1112 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiation track structure spherical targets energy deposition heavy ions HZE ionizing radiation Science Q
spellingShingle	radiation track structure spherical targets energy deposition heavy ions HZE ionizing radiation Science Q Ianik Plante Floriane Poignant Tony Slaba Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
description	To understand the biological effects of radiation, it is important to determine how ionizing radiation deposits energy in micrometric targets. The energy deposited in a target located in an irradiated tissue is a function of several factors such as the radiation type and the irradiated volume size. We simulated the energy deposited by energetic ions in spherical targets of 1, 2, 4, and 8 µm radii encompassed in irradiated parallelepiped volumes of various sizes using the stochastic radiation track structure code Relativistic Ion Tracks (RITRACKS). Because cells are usually part of a tissue when they are irradiated, electrons originating from radiation tracks in neighboring volumes also contribute to energy deposition in the target. To account for this contribution, we used periodic boundary conditions in the simulations. We found that the single-ion spectra of energy deposition in targets comprises two components: the direct ion hits to the targets, which is identical in all irradiation conditions, and the contribution of hits from electrons from neighboring volumes, which depends on the irradiated volume. We also calculated an analytical expression of the indirect hit contributions using the local effect model, which showed results similar to those obtained with RITRACKS.
format	article
author	Ianik Plante Floriane Poignant Tony Slaba
author_facet	Ianik Plante Floriane Poignant Tony Slaba
author_sort	Ianik Plante
title	Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
title_short	Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
title_full	Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
title_fullStr	Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
title_full_unstemmed	Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits
title_sort	track structure components: characterizing energy deposited in spherical cells from direct and peripheral hze ion hits
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/bc7c3b6500cf4027887248a58326d3e3
work_keys_str_mv	AT ianikplante trackstructurecomponentscharacterizingenergydepositedinsphericalcellsfromdirectandperipheralhzeionhits AT florianepoignant trackstructurecomponentscharacterizingenergydepositedinsphericalcellsfromdirectandperipheralhzeionhits AT tonyslaba trackstructurecomponentscharacterizingenergydepositedinsphericalcellsfromdirectandperipheralhzeionhits
_version_	1718411581671342080

Track Structure Components: Characterizing Energy Deposited in Spherical Cells from Direct and Peripheral HZE Ion Hits

Ejemplares similares