The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement.

Translational control and messenger RNA (mRNA) decay represent important control points in the regulation of gene expression. In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by decapping and 5'-3' exonucleolytic digestion of the mRNA. Proteins that activat...

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Autores principales: Thomas Sweet, Carrie Kovalak, Jeff Coller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/bc893de7687542c5a6e1098188b678ce
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