Manufacturing T cells in hollow fiber membrane bioreactors changes their programming and enhances their potency
Engineered T cell therapies have revolutionized modern oncology, however processes for manufacturing T cell therapies vary and the impact of manufacturing processes On the cell product is poorly understood. Herein, we have used a commercially available hollow fiber membrane bioreactor (HFMBR) operat...
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Autores principales: | Seung Mi Yoo, Vivan W.C. Lau, Craig Aarts, Bojana Bojovic, Gregory Steinberg, Joanne A. Hammill, Anna Dvorkin-Gheva, Raja Ghosh, Jonathan L. Bramson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bc99de84057540318ad448278d420b7a |
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