Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases
Abstract Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically upon different mammalian proteomes. He...
Guardado en:
Autores principales: | Amanda F. Asega, Milene C. Menezes, Dilza Trevisan-Silva, Daniela Cajado-Carvalho, Luciana Bertholim, Ana K. Oliveira, André Zelanis, Solange M. T. Serrano |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/bc9c2fbbe69d4ad8ab8d829248f79dbe |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins
por: Luciana Bertholim, et al.
Publicado: (2021) -
Functional variability of snake venom metalloproteinases: adaptive advantages in targeting different prey and implications for human envenomation.
por: Juliana L Bernardoni, et al.
Publicado: (2014) -
Involvement of von Willebrand factor and botrocetin in the thrombocytopenia induced by Bothrops jararaca snake venom.
por: Camila Martos Thomazini, et al.
Publicado: (2021) -
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα
por: Benjamin Xiaoyi Li, et al.
Publicado: (2021) -
The Proteoglycan Biglycan Modulates Platelet Adhesion and Thrombus Formation in a GPVI-Dependent Manner
por: Henrike Hoermann, et al.
Publicado: (2021)