Insulin resistance as a systemic player in renal pathology: a review
Current review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disor...
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Endocrinology Research Centre
2014
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oai:doaj.org-article:bca02f5c9dea43d693059e8d545ecb662021-11-14T09:00:18ZInsulin resistance as a systemic player in renal pathology: a review2072-03512072-037810.14341/DM2014147-56https://doaj.org/article/bca02f5c9dea43d693059e8d545ecb662014-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6313https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Current review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disorders, insulin resistance was shown to be an independent predictor of renal pathology, including such chronic conditions as urolithiasis, renal cysts and malignant renal neoplasms. Early detection and correction of insulin resistance is a promising approach to diagnostics, treatment and prevention of renal pathology.Igor Adamovich TyuzikovEndocrinology Research Centrearticleinsulin resistancechronic kidney diseaseurolithiasisrenal cystsrenal cancerpathogenesisdiagnosticsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 17, Iss 1, Pp 47-56 (2014) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN RU |
| topic |
insulin resistance chronic kidney disease urolithiasis renal cysts renal cancer pathogenesis diagnostics Nutritional diseases. Deficiency diseases RC620-627 |
| spellingShingle |
insulin resistance chronic kidney disease urolithiasis renal cysts renal cancer pathogenesis diagnostics Nutritional diseases. Deficiency diseases RC620-627 Igor Adamovich Tyuzikov Insulin resistance as a systemic player in renal pathology: a review |
| description |
Current review provides a multifaceted analysis of epidemiological, clinical and experimental evidence for insulin resistance as a systemic player in the development of renal pathology. We discuss both established and potential mechanisms for this effect. Aside from being a marker for glycemic disorders, insulin resistance was shown to be an independent predictor of renal pathology, including such chronic conditions as urolithiasis, renal cysts and malignant renal neoplasms. Early detection and correction of insulin resistance is a promising approach to diagnostics, treatment and prevention of renal pathology. |
| format |
article |
| author |
Igor Adamovich Tyuzikov |
| author_facet |
Igor Adamovich Tyuzikov |
| author_sort |
Igor Adamovich Tyuzikov |
| title |
Insulin resistance as a systemic player in renal pathology: a review |
| title_short |
Insulin resistance as a systemic player in renal pathology: a review |
| title_full |
Insulin resistance as a systemic player in renal pathology: a review |
| title_fullStr |
Insulin resistance as a systemic player in renal pathology: a review |
| title_full_unstemmed |
Insulin resistance as a systemic player in renal pathology: a review |
| title_sort |
insulin resistance as a systemic player in renal pathology: a review |
| publisher |
Endocrinology Research Centre |
| publishDate |
2014 |
| url |
https://doaj.org/article/bca02f5c9dea43d693059e8d545ecb66 |
| work_keys_str_mv |
AT igoradamovichtyuzikov insulinresistanceasasystemicplayerinrenalpathologyareview |
| _version_ |
1718429609319464960 |