Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study

Henock Duche,1 Adino Tesfahun Tsegay,2 Koku Sisay Tamirat2 1Ethiopia Public Health Institute, Addis Ababa, Ethiopia; 2Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaCorrespondence: Koku Sisay Tam...

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Autores principales:	Duche H, Tsegay AT, Tamirat KS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	breast cancer risk factors case-control study ethiopia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/bca0b963ec66498896529480b1667d4b
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spelling	oai:doaj.org-article:bca0b963ec66498896529480b1667d4b2021-12-02T11:36:26ZIdentifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study1179-1314https://doaj.org/article/bca0b963ec66498896529480b1667d4b2021-03-01T00:00:00Zhttps://www.dovepress.com/identifying-risk-factors-of-breast-cancer-among-women-attending-select-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Henock Duche,1 Adino Tesfahun Tsegay,2 Koku Sisay Tamirat2 1Ethiopia Public Health Institute, Addis Ababa, Ethiopia; 2Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaCorrespondence: Koku Sisay TamiratDepartment of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, EthiopiaEmail kokusisay23@gmail.comBackground: Breast cancer, one of the chronic diseases, is the most common cancer among women in the world. In Ethiopia, late-stage breast cancer is widely diagnosed and women have very little access to adequate medication, pain relief, or palliative care. In addition, there are few research on risk factors for breast cancer in Ethiopia. A safer way out of this is to concentrate on prevention; one of the prevention methods is to recognize risk factors sooner. The study therefore aimed to establish risk factors for breast cancer among women in hospitals in the city of Addis Ababa.Methods: Hospital-based, unmatched case-control research conducted in selected Addis Ababa hospitals from April to September 2017 (Case=110 and Control=110). Data were collected by standardized questionnaires for both cases and controls. Cases were initially detected by mammography screening accompanied by histopathological examinations, while controls were those women who were negative by mammogram testing, stress levels were assessed by perceived stress scale (PSS) and body mass index measured by WHO norm. Summary statistics Computed and binary logistic regression analysis to classify risk factors for breast cancer modified odds ratio (AOR) with 95% confidence interval (CI) calculated.Results: The participants’ mean age of was 43.80 years (SD ± 12.63) and 39.64 years (SD ± 12.91) for cases and controls, respectively. Physical activity (AOR=0.2, 95% CI: 0.10, 0.41) was correlated with lower probability of breast cancer, while never breastfeed (AOR=3.4, 95% CI: 1.21, 9.67); menopausal state (AOR=6.8, 95% CI: 1.92, 24.16), and body mass index above 25. 1 kg/m2 (AOR=5.9, 95% CI: 2.16, 16.48) were factors risk factors for breast cancer.Conclusion: This research shows the importance of physical exercise, breastfeeding, menopausal status, and nutritional status in the occurrence of breast cancer. Actions aimed at increasing physical activity, breastfeeding habits and keeping a balanced diet will help to minimize the incidence of breast cancer.Keywords: breast cancer, risk factors, case-control study, EthiopiaDuche HTsegay ATTamirat KSDove Medical Pressarticlebreast cancerrisk factorscase-control studyethiopiaNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol Volume 13, Pp 189-197 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	breast cancer risk factors case-control study ethiopia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	breast cancer risk factors case-control study ethiopia Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Duche H Tsegay AT Tamirat KS Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
description	Henock Duche,1 Adino Tesfahun Tsegay,2 Koku Sisay Tamirat2 1Ethiopia Public Health Institute, Addis Ababa, Ethiopia; 2Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, EthiopiaCorrespondence: Koku Sisay TamiratDepartment of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, EthiopiaEmail kokusisay23@gmail.comBackground: Breast cancer, one of the chronic diseases, is the most common cancer among women in the world. In Ethiopia, late-stage breast cancer is widely diagnosed and women have very little access to adequate medication, pain relief, or palliative care. In addition, there are few research on risk factors for breast cancer in Ethiopia. A safer way out of this is to concentrate on prevention; one of the prevention methods is to recognize risk factors sooner. The study therefore aimed to establish risk factors for breast cancer among women in hospitals in the city of Addis Ababa.Methods: Hospital-based, unmatched case-control research conducted in selected Addis Ababa hospitals from April to September 2017 (Case=110 and Control=110). Data were collected by standardized questionnaires for both cases and controls. Cases were initially detected by mammography screening accompanied by histopathological examinations, while controls were those women who were negative by mammogram testing, stress levels were assessed by perceived stress scale (PSS) and body mass index measured by WHO norm. Summary statistics Computed and binary logistic regression analysis to classify risk factors for breast cancer modified odds ratio (AOR) with 95% confidence interval (CI) calculated.Results: The participants’ mean age of was 43.80 years (SD ± 12.63) and 39.64 years (SD ± 12.91) for cases and controls, respectively. Physical activity (AOR=0.2, 95% CI: 0.10, 0.41) was correlated with lower probability of breast cancer, while never breastfeed (AOR=3.4, 95% CI: 1.21, 9.67); menopausal state (AOR=6.8, 95% CI: 1.92, 24.16), and body mass index above 25. 1 kg/m2 (AOR=5.9, 95% CI: 2.16, 16.48) were factors risk factors for breast cancer.Conclusion: This research shows the importance of physical exercise, breastfeeding, menopausal status, and nutritional status in the occurrence of breast cancer. Actions aimed at increasing physical activity, breastfeeding habits and keeping a balanced diet will help to minimize the incidence of breast cancer.Keywords: breast cancer, risk factors, case-control study, Ethiopia
format	article
author	Duche H Tsegay AT Tamirat KS
author_facet	Duche H Tsegay AT Tamirat KS
author_sort	Duche H
title	Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
title_short	Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
title_full	Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
title_fullStr	Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
title_full_unstemmed	Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study
title_sort	identifying risk factors of breast cancer among women attending selected hospitals of addis ababa city: hospital-based unmatched case-control study
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/bca0b963ec66498896529480b1667d4b
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Identifying Risk Factors of Breast Cancer Among Women Attending Selected Hospitals of Addis Ababa City: Hospital-Based Unmatched Case-Control Study

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