Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis

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Estrogen Receptor 1 Inhibition of Wnt/β-Catenin Signaling Contributes to Sex Differences in Hepatocarcinogenesis

BackgroundHepatocellular Carcinoma (HCC) is a sexually dimorphic cancer, with female sex being independently protective against HCC incidence and progression. The aim of our study was to understand the mechanism of estrogen receptor signaling in driving sex differences in hepatocarcinogenesis.Method...

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Autores principales:	Mamatha Bhat, Elisa Pasini, Chiara Pastrello, Marc Angeli, Cristina Baciu, Mark Abovsky, Angella Coffee, Oyedele Adeyi, Max Kotlyar, Igor Jurisica
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	estrogen hepatocellular carcinoma high-throughput network analysis Wnt/b-catenin ESR1 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/bcad94a7b6a3471bb30f1db3e5daad2f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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