Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter

The human serotonin transporter (SERT) mediates the uptake of neurotransmitters to terminate neuronal signalling. Here the authors use single-molecule imaging to get insight into the molecular origin of SERT oligomerization and their pre-set stoichiometry at the plasma membrane.

Saved in:
Bibliographic Details
Main Authors: Andreas Anderluh, Tina Hofmaier, Enrico Klotzsch, Oliver Kudlacek, Thomas Stockner, Harald H. Sitte, Gerhard J. Schütz
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/bcb1096f3d314ab090f13b2d7e457d58
Tags: Add Tag
No Tags, Be the first to tag this record!