Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment

Oxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium di...

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Autores principales:	K Y Abdel-Halim, S R Osman, H T M El-Danasoury, R M Ziada
Formato:	article
Lenguaje:	EN
Publicado:	University of Modena and Reggio Emilia 2021
Materias:	nanomaterials oxidative stress terrestrial Helix aspersa dermal toxicity Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/bcb309bdaa0844078e30d135a61118d2
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spelling	oai:doaj.org-article:bcb309bdaa0844078e30d135a61118d22021-12-02T18:35:55ZPotential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment10.25431/1824-307X/isj.v18i1.119-1291824-307Xhttps://doaj.org/article/bcb309bdaa0844078e30d135a61118d22021-10-01T00:00:00Zhttps://www.isj.unimore.it/index.php/ISJ/article/view/694https://doaj.org/toc/1824-307X Oxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium dioxide nanoparticles (TiO2NPs), and 8.0 and 1.6 µg snail-1 for Single-Walled Carbon Nanotubes (SWCNTs) during 48 h. The results indicated that, both nanomaterials (NMs) induced significant increases in malondialdehyde (MDA) as biomarker for lipid peroxidation (LPO). However, SWCNTs induced significant decline in reduced glutathione (GSH) content compared with the control. Catalase (CAT) activity significantly increased for the all treatments greater than the control. On the other hand, activities of glutathione-S-transferase (GST) and glutathione peroxidase (GPx) slightly decreased for both NMs. Nanoparticles (NPs) of TiO2 increased activity of glutathione reductase (GR) in both haemolymph and digestive gland homogenates, while SWCNTs treatments exhibited activities did not exceed the value of the control (0.08 U mg-1 protein). The present findings indicate that, alterations of antioxidant enzymes activity and levels of MDA and GSH are recognized to oxidative stress. Consequently, the use of snail, H. aspersa can offer a respectable sentinel model to assess ecotoxicological effects of NMs on the gastropods. K Y Abdel-HalimS R OsmanH T M El-DanasouryR M ZiadaUniversity of Modena and Reggio Emiliaarticlenanomaterialsoxidative stressterrestrialHelix aspersadermal toxicityBiology (General)QH301-705.5ENInvertebrate Survival Journal, Vol 18, Iss 1 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanomaterials oxidative stress terrestrial Helix aspersa dermal toxicity Biology (General) QH301-705.5
spellingShingle	nanomaterials oxidative stress terrestrial Helix aspersa dermal toxicity Biology (General) QH301-705.5 K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
description	Oxidative stress represents a main regularly informed mechanism of nanoparticles (NPs) toxicity. The present work was designed to evaluate the oxidative stress in haemolymph and digestive gland of snail Helix aspersa after exposure to different dermal doses: 10.8 and 2.17 µg snail-1 for titanium dioxide nanoparticles (TiO2NPs), and 8.0 and 1.6 µg snail-1 for Single-Walled Carbon Nanotubes (SWCNTs) during 48 h. The results indicated that, both nanomaterials (NMs) induced significant increases in malondialdehyde (MDA) as biomarker for lipid peroxidation (LPO). However, SWCNTs induced significant decline in reduced glutathione (GSH) content compared with the control. Catalase (CAT) activity significantly increased for the all treatments greater than the control. On the other hand, activities of glutathione-S-transferase (GST) and glutathione peroxidase (GPx) slightly decreased for both NMs. Nanoparticles (NPs) of TiO2 increased activity of glutathione reductase (GR) in both haemolymph and digestive gland homogenates, while SWCNTs treatments exhibited activities did not exceed the value of the control (0.08 U mg-1 protein). The present findings indicate that, alterations of antioxidant enzymes activity and levels of MDA and GSH are recognized to oxidative stress. Consequently, the use of snail, H. aspersa can offer a respectable sentinel model to assess ecotoxicological effects of NMs on the gastropods.
format	article
author	K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada
author_facet	K Y Abdel-Halim S R Osman H T M El-Danasoury R M Ziada
author_sort	K Y Abdel-Halim
title	Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
title_short	Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
title_full	Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
title_fullStr	Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
title_full_unstemmed	Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
title_sort	potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment
publisher	University of Modena and Reggio Emilia
publishDate	2021
url	https://doaj.org/article/bcb309bdaa0844078e30d135a61118d2
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Potential toxic effects of titanium dioxide nanoparticles and carbon nanotubes on land snail Helix aspersa: use of oxidative stress as a reliable biomarker for ecotoxicology assessment

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