Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies.
It is of great interest and potential to discover causal relationships between pairs of exposures and outcomes using genetic variants as instrumental variables (IVs) to deal with hidden confounding in observational studies. Two most popular approaches are Mendelian randomization (MR), which usually...
Guardado en:
Autores principales: | Yangqing Deng, Wei Pan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/bcc004943ed44a448c2aa11b742247eb |
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