Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies.
It is of great interest and potential to discover causal relationships between pairs of exposures and outcomes using genetic variants as instrumental variables (IVs) to deal with hidden confounding in observational studies. Two most popular approaches are Mendelian randomization (MR), which usually...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/bcc004943ed44a448c2aa11b742247eb |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!