Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region

Background. In cases of tuberculosis in children, contacts with patients with drug-resistant forms are often detected. Treatment and prevention of the disease is based on these data and adherence to treatment. Aims. To analyze the social status of the family of children with tuberculosis, clinical f...

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Autores principales:	E. Y. Zorkaltseva, S. V. Pugacheva, A. S. Tolstykh
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	tuberculosis in children drug resistance of mycobacterium tuberculosis social factors Science Q
Acceso en línea:	https://doaj.org/article/bcc18962a83f486cb18323f43e117c38
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spelling	oai:doaj.org-article:bcc18962a83f486cb18323f43e117c382021-11-23T06:14:38ZMedical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region2541-94202587-959610.12737/article_5a3a0eabd5ee12.61732822https://doaj.org/article/bcc18962a83f486cb18323f43e117c382017-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/524https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. In cases of tuberculosis in children, contacts with patients with drug-resistant forms are often detected. Treatment and prevention of the disease is based on these data and adherence to treatment. Aims. To analyze the social status of the family of children with tuberculosis, clinical forms and drug resistance of MBT in patients who are sources of infection in the outbreak for adequate planning of preventive treatment of contact and treatment of children with tuberculosis. Materials and methods. The study involved 150 children with tuberculosis treated in a hospital in 2009-2012 and 142 children - in 2015-2017. We studied social factors and drug resistance of Mycobacterium tuberculosis in adult patients - sources to child transmission. Drug resistance of MBT cultures was determined by Löwenstein - Jensen medium and automated system BACTEC MGIT 960. Results. 50.0 % of children with tuberculosis are patients of preschool age, 33.0 % of children aged under 3 years. From 2009-2012 to 2015-2017 the proportion of socially disadvantaged families fell from 68.0 % to 45.1 %. At the same time the proportion of children with tuberculosis, contracted from a known contact decreased from 70.0 % to 57.0 %. Often children get infected from mother or from several close relatives (mother, father, grandfather, grandmother), TB patients source of infection of children are often diagnosed with infiltrative (21.9-38.3 %) and fibro-cavernous tuberculosis (17.0-21.0 %). To 2015-2017 multi-drug resistance in the nidi was recorded at 52.2 %. The development of tuberculosis in children was facilitated by the defects of preventative measures: absence of BCG vaccination (from 9.0 to 14.0 % of children), the absence of preventive treatment (55.3-67.5 %).E. Y. ZorkaltsevaS. V. PugachevaA. S. TolstykhScientific Сentre for Family Health and Human Reproduction Problemsarticletuberculosis in childrendrug resistance of mycobacterium tuberculosissocial factorsScienceQRUActa Biomedica Scientifica, Vol 2, Iss 5(2), Pp 147-150 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	tuberculosis in children drug resistance of mycobacterium tuberculosis social factors Science Q
spellingShingle	tuberculosis in children drug resistance of mycobacterium tuberculosis social factors Science Q E. Y. Zorkaltseva S. V. Pugacheva A. S. Tolstykh Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
description	Background. In cases of tuberculosis in children, contacts with patients with drug-resistant forms are often detected. Treatment and prevention of the disease is based on these data and adherence to treatment. Aims. To analyze the social status of the family of children with tuberculosis, clinical forms and drug resistance of MBT in patients who are sources of infection in the outbreak for adequate planning of preventive treatment of contact and treatment of children with tuberculosis. Materials and methods. The study involved 150 children with tuberculosis treated in a hospital in 2009-2012 and 142 children - in 2015-2017. We studied social factors and drug resistance of Mycobacterium tuberculosis in adult patients - sources to child transmission. Drug resistance of MBT cultures was determined by Löwenstein - Jensen medium and automated system BACTEC MGIT 960. Results. 50.0 % of children with tuberculosis are patients of preschool age, 33.0 % of children aged under 3 years. From 2009-2012 to 2015-2017 the proportion of socially disadvantaged families fell from 68.0 % to 45.1 %. At the same time the proportion of children with tuberculosis, contracted from a known contact decreased from 70.0 % to 57.0 %. Often children get infected from mother or from several close relatives (mother, father, grandfather, grandmother), TB patients source of infection of children are often diagnosed with infiltrative (21.9-38.3 %) and fibro-cavernous tuberculosis (17.0-21.0 %). To 2015-2017 multi-drug resistance in the nidi was recorded at 52.2 %. The development of tuberculosis in children was facilitated by the defects of preventative measures: absence of BCG vaccination (from 9.0 to 14.0 % of children), the absence of preventive treatment (55.3-67.5 %).
format	article
author	E. Y. Zorkaltseva S. V. Pugacheva A. S. Tolstykh
author_facet	E. Y. Zorkaltseva S. V. Pugacheva A. S. Tolstykh
author_sort	E. Y. Zorkaltseva
title	Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
title_short	Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
title_full	Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
title_fullStr	Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
title_full_unstemmed	Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region
title_sort	medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the irkutsk region
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/bcc18962a83f486cb18323f43e117c38
work_keys_str_mv	AT eyzorkaltseva medicalandsocialcharacteristicsofchildrenwithtuberculosisinconditionsofsocialinsufficiencyintheirkutskregion AT svpugacheva medicalandsocialcharacteristicsofchildrenwithtuberculosisinconditionsofsocialinsufficiencyintheirkutskregion AT astolstykh medicalandsocialcharacteristicsofchildrenwithtuberculosisinconditionsofsocialinsufficiencyintheirkutskregion
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Medical and social characteristics of children with tuberculosis in conditions of social insufficiency in the Irkutsk region

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