Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density

Abstract Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enro...

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Autores principales:	Chia-Chi Yen, Wei-Chun Lin, Tzu-Hao Wang, Guan-Fan Chen, Da-Ying Chou, Dian-Min Lin, Shu-Yuan Lin, Min-Ho Chan, Jia-Ming Wu, Chin-Dar Tseng, Yu-Jie Huang, Tsair-Fwu Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bcc5448f5ef04b8f9251c51254fd0a5f
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spelling	oai:doaj.org-article:bcc5448f5ef04b8f9251c51254fd0a5f2021-12-02T18:49:23ZPre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density10.1038/s41598-021-95261-72045-2322https://doaj.org/article/bcc5448f5ef04b8f9251c51254fd0a5f2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95261-7https://doaj.org/toc/2045-2322Abstract Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden’s Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.Chia-Chi YenWei-Chun LinTzu-Hao WangGuan-Fan ChenDa-Ying ChouDian-Min LinShu-Yuan LinMin-Ho ChanJia-Ming WuChin-Dar TsengYu-Jie HuangTsair-Fwu LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chia-Chi Yen Wei-Chun Lin Tzu-Hao Wang Guan-Fan Chen Da-Ying Chou Dian-Min Lin Shu-Yuan Lin Min-Ho Chan Jia-Ming Wu Chin-Dar Tseng Yu-Jie Huang Tsair-Fwu Lee Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
description	Abstract Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden’s Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.
format	article
author	Chia-Chi Yen Wei-Chun Lin Tzu-Hao Wang Guan-Fan Chen Da-Ying Chou Dian-Min Lin Shu-Yuan Lin Min-Ho Chan Jia-Ming Wu Chin-Dar Tseng Yu-Jie Huang Tsair-Fwu Lee
author_facet	Chia-Chi Yen Wei-Chun Lin Tzu-Hao Wang Guan-Fan Chen Da-Ying Chou Dian-Min Lin Shu-Yuan Lin Min-Ho Chan Jia-Ming Wu Chin-Dar Tseng Yu-Jie Huang Tsair-Fwu Lee
author_sort	Chia-Chi Yen
title	Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
title_short	Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
title_full	Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
title_fullStr	Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
title_full_unstemmed	Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density
title_sort	pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy x-ray absorptiometry bone density
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bcc5448f5ef04b8f9251c51254fd0a5f
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Pre-screening for osteoporosis with calcaneus quantitative ultrasound and dual-energy X-ray absorptiometry bone density

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