The genetic relationship between epilepsy and hemiplegic migraine
Yiqing Huang,1 Hai Xiao,1 Xingyue Qin,1 Yuan Nong,1 Donghua Zou,2 Yuan Wu3 1Department of Neurology, Guigang City People’s Hospital and the Eighth Affiliated Hospital of Guangxi Medical University, Guigang, People’s Republic of China; 2Department of Neurology, The Fifth Affiliat...
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Dove Medical Press
2017
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oai:doaj.org-article:bcc71c83b7b2434b88968ac3928cf1ed2021-12-02T06:32:13ZThe genetic relationship between epilepsy and hemiplegic migraine1178-2021https://doaj.org/article/bcc71c83b7b2434b88968ac3928cf1ed2017-04-01T00:00:00Zhttps://www.dovepress.com/the-genetic-relationship-between-epilepsy-and-hemiplegic-migraine-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Yiqing Huang,1 Hai Xiao,1 Xingyue Qin,1 Yuan Nong,1 Donghua Zou,2 Yuan Wu3 1Department of Neurology, Guigang City People’s Hospital and the Eighth Affiliated Hospital of Guangxi Medical University, Guigang, People’s Republic of China; 2Department of Neurology, The Fifth Affiliated Hospital of Guangxi Medical University and the First People’s Hospital of Nanning, Nanning, People’s Republic of China; 3Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China Abstract: Epilepsy and migraine are common diseases of the nervous system and share genetic and pathophysiological mechanisms. Familial hemiplegic migraine is an autosomal dominant disease. It is often used as a model of migraine. Four genes often contain one or more mutations in both epilepsy and hemiplegic migraine patients (ie, CACNA1A, ATP1A2, SCN1A, and PRRT2). A better understanding of the shared genetics of epilepsy and hemiplegic migraine may reveal new strategic directions for research and treatment of both the disorders. Keywords: epilepsy, migraine, CACNA1A, ATP1A2, SCN1AHuang YXiao HQin XNong YZou DWu YDove Medical PressarticleEpilepsymigraineCACNA1AATP1A2SCN1ANeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 1175-1179 (2017) |
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DOAJ |
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DOAJ |
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EN |
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Epilepsy migraine CACNA1A ATP1A2 SCN1A Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Epilepsy migraine CACNA1A ATP1A2 SCN1A Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Huang Y Xiao H Qin X Nong Y Zou D Wu Y The genetic relationship between epilepsy and hemiplegic migraine |
| description |
Yiqing Huang,1 Hai Xiao,1 Xingyue Qin,1 Yuan Nong,1 Donghua Zou,2 Yuan Wu3 1Department of Neurology, Guigang City People’s Hospital and the Eighth Affiliated Hospital of Guangxi Medical University, Guigang, People’s Republic of China; 2Department of Neurology, The Fifth Affiliated Hospital of Guangxi Medical University and the First People’s Hospital of Nanning, Nanning, People’s Republic of China; 3Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China Abstract: Epilepsy and migraine are common diseases of the nervous system and share genetic and pathophysiological mechanisms. Familial hemiplegic migraine is an autosomal dominant disease. It is often used as a model of migraine. Four genes often contain one or more mutations in both epilepsy and hemiplegic migraine patients (ie, CACNA1A, ATP1A2, SCN1A, and PRRT2). A better understanding of the shared genetics of epilepsy and hemiplegic migraine may reveal new strategic directions for research and treatment of both the disorders. Keywords: epilepsy, migraine, CACNA1A, ATP1A2, SCN1A |
| format |
article |
| author |
Huang Y Xiao H Qin X Nong Y Zou D Wu Y |
| author_facet |
Huang Y Xiao H Qin X Nong Y Zou D Wu Y |
| author_sort |
Huang Y |
| title |
The genetic relationship between epilepsy and hemiplegic migraine |
| title_short |
The genetic relationship between epilepsy and hemiplegic migraine |
| title_full |
The genetic relationship between epilepsy and hemiplegic migraine |
| title_fullStr |
The genetic relationship between epilepsy and hemiplegic migraine |
| title_full_unstemmed |
The genetic relationship between epilepsy and hemiplegic migraine |
| title_sort |
genetic relationship between epilepsy and hemiplegic migraine |
| publisher |
Dove Medical Press |
| publishDate |
2017 |
| url |
https://doaj.org/article/bcc71c83b7b2434b88968ac3928cf1ed |
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