Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig

DNA 6mA is a poorly understood epigenetic mark present at a low abundance in eukaryotic genomes. Here the authors observe high levels in zebrafish and pig during early embryogenesis enriched to repetitive regions of the genome and followed by attenuation during development.

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Bibliographic Details
Main Authors: Jianzhao Liu, Yuanxiang Zhu, Guan-Zheng Luo, Xinxia Wang, Yanan Yue, Xiaona Wang, Xin Zong, Kai Chen, Hang Yin, Ye Fu, Dali Han, Yizhen Wang, Dahua Chen, Chuan He
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/bcd384b0547f495d83ee82187a8598d4
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Summary:DNA 6mA is a poorly understood epigenetic mark present at a low abundance in eukaryotic genomes. Here the authors observe high levels in zebrafish and pig during early embryogenesis enriched to repetitive regions of the genome and followed by attenuation during development.