Mesenchymal stromal cells as carriers of IL-12 reduce primary and metastatic tumors of murine melanoma

Mesenchymal stromal cells as carriers of IL-12 reduce primary and metastatic tumors of murine melanoma

Abstract Due to immunosuppressive properties and confirmed tropism towards cancer cells mesenchymal stromal cells (MSC) have been used in many trials. In our study we used these cells as carriers of IL-12 in the treatment of mice with primary and metastatic B16-F10 melanomas. IL-12 has confirmed ant...

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Main Authors: Natalia Kułach, Ewelina Pilny, Tomasz Cichoń, Justyna Czapla, Magdalena Jarosz-Biej, Marek Rusin, Alina Drzyzga, Sybilla Matuszczak, Stanisław Szala, Ryszard Smolarczyk
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/bcd4d466f3a84e96830b0f5ae3e9063f
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https://doaj.org/article/bcd4d466f3a84e96830b0f5ae3e9063f

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