Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids

Identification of gene targets is one of the major challenges to construct superior microbial cell factory for chemical synthesis. Here, the authors employ CRISPRi and omics analyses for genome-scale target genes identification for high-titer production of free fatty acids in E. coli.

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Autores principales:	Lixia Fang, Jie Fan, Shulei Luo, Yaru Chen, Congya Wang, Yingxiu Cao, Hao Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bcd8eeab148f4089b32caa0ff6558bad
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spelling	oai:doaj.org-article:bcd8eeab148f4089b32caa0ff6558bad2021-12-02T15:10:47ZGenome-scale target identification in Escherichia coli for high-titer production of free fatty acids10.1038/s41467-021-25243-w2041-1723https://doaj.org/article/bcd8eeab148f4089b32caa0ff6558bad2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25243-whttps://doaj.org/toc/2041-1723Identification of gene targets is one of the major challenges to construct superior microbial cell factory for chemical synthesis. Here, the authors employ CRISPRi and omics analyses for genome-scale target genes identification for high-titer production of free fatty acids in E. coli.Lixia FangJie FanShulei LuoYaru ChenCongya WangYingxiu CaoHao SongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lixia Fang Jie Fan Shulei Luo Yaru Chen Congya Wang Yingxiu Cao Hao Song Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
description	Identification of gene targets is one of the major challenges to construct superior microbial cell factory for chemical synthesis. Here, the authors employ CRISPRi and omics analyses for genome-scale target genes identification for high-titer production of free fatty acids in E. coli.
format	article
author	Lixia Fang Jie Fan Shulei Luo Yaru Chen Congya Wang Yingxiu Cao Hao Song
author_facet	Lixia Fang Jie Fan Shulei Luo Yaru Chen Congya Wang Yingxiu Cao Hao Song
author_sort	Lixia Fang
title	Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
title_short	Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
title_full	Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
title_fullStr	Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
title_full_unstemmed	Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
title_sort	genome-scale target identification in escherichia coli for high-titer production of free fatty acids
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/bcd8eeab148f4089b32caa0ff6558bad
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Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids

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