Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.

Proteomic studies of spermatozoa have identified a large catalog of integral sperm proteins. Rapid evolution of these proteins may underlie adaptive changes of sperm traits involved in different events leading to fertilization, although the selective forces underlying such rapid evolution are not we...

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Autores principales:	Alberto Vicens, Lena Lüke, Eduardo R S Roldan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bcdd70d8eea54f6c813f1add9a4364e4
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spelling	oai:doaj.org-article:bcdd70d8eea54f6c813f1add9a4364e42021-11-18T08:29:13ZProteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.1932-620310.1371/journal.pone.0091302https://doaj.org/article/bcdd70d8eea54f6c813f1add9a4364e42014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24608277/?tool=EBIhttps://doaj.org/toc/1932-6203Proteomic studies of spermatozoa have identified a large catalog of integral sperm proteins. Rapid evolution of these proteins may underlie adaptive changes of sperm traits involved in different events leading to fertilization, although the selective forces underlying such rapid evolution are not well understood. A variety of selective forces may differentially affect several steps ending in fertilization, thus resulting in a compartmentalized adaptation of sperm proteins. Here we analyzed the evolution of genes associated to various events in the sperm's life, from sperm formation to sperm-egg interaction. Evolutionary analyses were performed on gene sequences from 17 mouse strains whose genomes have been sequenced. Four of these are derived from wild Mus musculus, M. domesticus, M. castaneus and M. spretus. We found a higher proportion of genes exhibiting a signature of positive selection among those related to sperm motility and sperm-egg interaction. Furthermore, sperm proteins involved in sperm-egg interaction exhibited accelerated evolution in comparison to those involved in other events. Thus, we identified a large set of candidate proteins for future comparative analyses of genotype-phenotype associations in spermatozoa of species subjected to different sexual selection pressures. Adaptive evolution of proteins involved in motility could be driven by sperm competition, since this selective force is known to increase the proportion of motile sperm and their swimming velocity. On the other hand, sperm proteins involved in gamete interaction could be coevolving with their egg partners through episodes of sexual selection or sexual conflict resulting in species-specific sperm-egg interactions and barriers preventing interspecies fertilization.Alberto VicensLena LükeEduardo R S RoldanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 3, p e91302 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alberto Vicens Lena Lüke Eduardo R S Roldan Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
description	Proteomic studies of spermatozoa have identified a large catalog of integral sperm proteins. Rapid evolution of these proteins may underlie adaptive changes of sperm traits involved in different events leading to fertilization, although the selective forces underlying such rapid evolution are not well understood. A variety of selective forces may differentially affect several steps ending in fertilization, thus resulting in a compartmentalized adaptation of sperm proteins. Here we analyzed the evolution of genes associated to various events in the sperm's life, from sperm formation to sperm-egg interaction. Evolutionary analyses were performed on gene sequences from 17 mouse strains whose genomes have been sequenced. Four of these are derived from wild Mus musculus, M. domesticus, M. castaneus and M. spretus. We found a higher proportion of genes exhibiting a signature of positive selection among those related to sperm motility and sperm-egg interaction. Furthermore, sperm proteins involved in sperm-egg interaction exhibited accelerated evolution in comparison to those involved in other events. Thus, we identified a large set of candidate proteins for future comparative analyses of genotype-phenotype associations in spermatozoa of species subjected to different sexual selection pressures. Adaptive evolution of proteins involved in motility could be driven by sperm competition, since this selective force is known to increase the proportion of motile sperm and their swimming velocity. On the other hand, sperm proteins involved in gamete interaction could be coevolving with their egg partners through episodes of sexual selection or sexual conflict resulting in species-specific sperm-egg interactions and barriers preventing interspecies fertilization.
format	article
author	Alberto Vicens Lena Lüke Eduardo R S Roldan
author_facet	Alberto Vicens Lena Lüke Eduardo R S Roldan
author_sort	Alberto Vicens
title	Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
title_short	Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
title_full	Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
title_fullStr	Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
title_full_unstemmed	Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
title_sort	proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/bcdd70d8eea54f6c813f1add9a4364e4
work_keys_str_mv	AT albertovicens proteinsinvolvedinmotilityandspermegginteractionevolvemorerapidlyinmousespermatozoa AT lenaluke proteinsinvolvedinmotilityandspermegginteractionevolvemorerapidlyinmousespermatozoa AT eduardorsroldan proteinsinvolvedinmotilityandspermegginteractionevolvemorerapidlyinmousespermatozoa
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Proteins involved in motility and sperm-egg interaction evolve more rapidly in mouse spermatozoa.

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