miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.

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Autores principales:	Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bce2ee1a64f046a383d8e6d4a3be7c1a
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spelling	oai:doaj.org-article:bce2ee1a64f046a383d8e6d4a3be7c1a2021-12-02T16:50:05ZmiR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression10.1038/s41467-018-07786-72041-1723https://doaj.org/article/bce2ee1a64f046a383d8e6d4a3be7c1a2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07786-7https://doaj.org/toc/2041-1723miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.Paul N. ValdmanisHak Kyun KimKirk ChuFeijie ZhangJianpeng XuElizabeth M. MundingJia ShenMark A. KayNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paul N. Valdmanis Hak Kyun Kim Kirk Chu Feijie Zhang Jianpeng Xu Elizabeth M. Munding Jia Shen Mark A. Kay miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
description	miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.
format	article
author	Paul N. Valdmanis Hak Kyun Kim Kirk Chu Feijie Zhang Jianpeng Xu Elizabeth M. Munding Jia Shen Mark A. Kay
author_facet	Paul N. Valdmanis Hak Kyun Kim Kirk Chu Feijie Zhang Jianpeng Xu Elizabeth M. Munding Jia Shen Mark A. Kay
author_sort	Paul N. Valdmanis
title	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
title_short	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
title_full	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
title_fullStr	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
title_full_unstemmed	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
title_sort	mir-122 removal in the liver activates imprinted micrornas and enables more effective microrna-mediated gene repression
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/bce2ee1a64f046a383d8e6d4a3be7c1a
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miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

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