Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established i...
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Elsevier
2021
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oai:doaj.org-article:bcee1939443d406fb2ec6f6a0d2724262021-12-02T05:00:18ZConstruction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male1873-506110.1016/j.scr.2021.102608https://doaj.org/article/bcee1939443d406fb2ec6f6a0d2724262021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1873506121004554https://doaj.org/toc/1873-5061We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established iPSC line using non-integrated reprogramming technology. The iPSC line showed normal karyotype, expressed pluripotency markers and differentiated into three germ layers in vivo. The cell line will serve as an available control in the research of pathological mechanisms of early-onset neurological diseases.Shaohua LiYunchao WangHuifang SunZhuoya WangQi ZhangYanlin WangJing YangChanghe ShiYanpeng YuanHao WangLiyuan FanZhuo LiYuming XuElsevierarticleBiology (General)QH301-705.5ENStem Cell Research, Vol 57, Iss , Pp 102608- (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Shaohua Li Yunchao Wang Huifang Sun Zhuoya Wang Qi Zhang Yanlin Wang Jing Yang Changhe Shi Yanpeng Yuan Hao Wang Liyuan Fan Zhuo Li Yuming Xu Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
description |
We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established iPSC line using non-integrated reprogramming technology. The iPSC line showed normal karyotype, expressed pluripotency markers and differentiated into three germ layers in vivo. The cell line will serve as an available control in the research of pathological mechanisms of early-onset neurological diseases. |
format |
article |
author |
Shaohua Li Yunchao Wang Huifang Sun Zhuoya Wang Qi Zhang Yanlin Wang Jing Yang Changhe Shi Yanpeng Yuan Hao Wang Liyuan Fan Zhuo Li Yuming Xu |
author_facet |
Shaohua Li Yunchao Wang Huifang Sun Zhuoya Wang Qi Zhang Yanlin Wang Jing Yang Changhe Shi Yanpeng Yuan Hao Wang Liyuan Fan Zhuo Li Yuming Xu |
author_sort |
Shaohua Li |
title |
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
title_short |
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
title_full |
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
title_fullStr |
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
title_full_unstemmed |
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male |
title_sort |
construction of induced pluripotent stem cell line (zzui031-a) of a healthy young chinese han male |
publisher |
Elsevier |
publishDate |
2021 |
url |
https://doaj.org/article/bcee1939443d406fb2ec6f6a0d272426 |
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