Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male

We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established i...

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Autores principales: Shaohua Li, Yunchao Wang, Huifang Sun, Zhuoya Wang, Qi Zhang, Yanlin Wang, Jing Yang, Changhe Shi, Yanpeng Yuan, Hao Wang, Liyuan Fan, Zhuo Li, Yuming Xu
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Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/bcee1939443d406fb2ec6f6a0d272426
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spelling oai:doaj.org-article:bcee1939443d406fb2ec6f6a0d2724262021-12-02T05:00:18ZConstruction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male1873-506110.1016/j.scr.2021.102608https://doaj.org/article/bcee1939443d406fb2ec6f6a0d2724262021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1873506121004554https://doaj.org/toc/1873-5061We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established iPSC line using non-integrated reprogramming technology. The iPSC line showed normal karyotype, expressed pluripotency markers and differentiated into three germ layers in vivo. The cell line will serve as an available control in the research of pathological mechanisms of early-onset neurological diseases.Shaohua LiYunchao WangHuifang SunZhuoya WangQi ZhangYanlin WangJing YangChanghe ShiYanpeng YuanHao WangLiyuan FanZhuo LiYuming XuElsevierarticleBiology (General)QH301-705.5ENStem Cell Research, Vol 57, Iss , Pp 102608- (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Shaohua Li
Yunchao Wang
Huifang Sun
Zhuoya Wang
Qi Zhang
Yanlin Wang
Jing Yang
Changhe Shi
Yanpeng Yuan
Hao Wang
Liyuan Fan
Zhuo Li
Yuming Xu
Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
description We have successively constructed several induced pluripotent stem cell (iPSC) lines of middle-aged and elderly male, but cell samples from young donors are still scarce. In this project, we recruited a healthy 29-year-old Chinese Han male, obtained his skin fibroblasts and successfully established iPSC line using non-integrated reprogramming technology. The iPSC line showed normal karyotype, expressed pluripotency markers and differentiated into three germ layers in vivo. The cell line will serve as an available control in the research of pathological mechanisms of early-onset neurological diseases.
format article
author Shaohua Li
Yunchao Wang
Huifang Sun
Zhuoya Wang
Qi Zhang
Yanlin Wang
Jing Yang
Changhe Shi
Yanpeng Yuan
Hao Wang
Liyuan Fan
Zhuo Li
Yuming Xu
author_facet Shaohua Li
Yunchao Wang
Huifang Sun
Zhuoya Wang
Qi Zhang
Yanlin Wang
Jing Yang
Changhe Shi
Yanpeng Yuan
Hao Wang
Liyuan Fan
Zhuo Li
Yuming Xu
author_sort Shaohua Li
title Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
title_short Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
title_full Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
title_fullStr Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
title_full_unstemmed Construction of induced pluripotent stem cell line (ZZUi031-A) of a healthy young Chinese Han male
title_sort construction of induced pluripotent stem cell line (zzui031-a) of a healthy young chinese han male
publisher Elsevier
publishDate 2021
url https://doaj.org/article/bcee1939443d406fb2ec6f6a0d272426
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