High-resolution NMR studies of antibiotics in cellular membranes

High-resolution NMR studies of antibiotics in cellular membranes

Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.

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Bibliographic Details
Main Authors: João Medeiros-Silva, Shehrazade Jekhmane, Alessandra Lucini Paioni, Katarzyna Gawarecka, Marc Baldus, Ewa Swiezewska, Eefjan Breukink, Markus Weingarth
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/bd00728712b046ff860cffd2d2e6f5cd
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Summary:Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.

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