High-resolution NMR studies of antibiotics in cellular membranes

High-resolution NMR studies of antibiotics in cellular membranes

Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.

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Autores principales: João Medeiros-Silva, Shehrazade Jekhmane, Alessandra Lucini Paioni, Katarzyna Gawarecka, Marc Baldus, Ewa Swiezewska, Eefjan Breukink, Markus Weingarth
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/bd00728712b046ff860cffd2d2e6f5cd
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spelling oai:doaj.org-article:bd00728712b046ff860cffd2d2e6f5cd2021-12-02T16:50:11ZHigh-resolution NMR studies of antibiotics in cellular membranes10.1038/s41467-018-06314-x2041-1723https://doaj.org/article/bd00728712b046ff860cffd2d2e6f5cd2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06314-xhttps://doaj.org/toc/2041-1723Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.João Medeiros-SilvaShehrazade JekhmaneAlessandra Lucini PaioniKatarzyna GawareckaMarc BaldusEwa SwiezewskaEefjan BreukinkMarkus WeingarthNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
João Medeiros-Silva
Shehrazade Jekhmane
Alessandra Lucini Paioni
Katarzyna Gawarecka
Marc Baldus
Ewa Swiezewska
Eefjan Breukink
Markus Weingarth
High-resolution NMR studies of antibiotics in cellular membranes
description Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
format article
author João Medeiros-Silva
Shehrazade Jekhmane
Alessandra Lucini Paioni
Katarzyna Gawarecka
Marc Baldus
Ewa Swiezewska
Eefjan Breukink
Markus Weingarth
author_facet João Medeiros-Silva
Shehrazade Jekhmane
Alessandra Lucini Paioni
Katarzyna Gawarecka
Marc Baldus
Ewa Swiezewska
Eefjan Breukink
Markus Weingarth
author_sort João Medeiros-Silva
title High-resolution NMR studies of antibiotics in cellular membranes
title_short High-resolution NMR studies of antibiotics in cellular membranes
title_full High-resolution NMR studies of antibiotics in cellular membranes
title_fullStr High-resolution NMR studies of antibiotics in cellular membranes
title_full_unstemmed High-resolution NMR studies of antibiotics in cellular membranes
title_sort high-resolution nmr studies of antibiotics in cellular membranes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/bd00728712b046ff860cffd2d2e6f5cd
work_keys_str_mv AT joaomedeirossilva highresolutionnmrstudiesofantibioticsincellularmembranes
AT shehrazadejekhmane highresolutionnmrstudiesofantibioticsincellularmembranes
AT alessandralucinipaioni highresolutionnmrstudiesofantibioticsincellularmembranes
AT katarzynagawarecka highresolutionnmrstudiesofantibioticsincellularmembranes
AT marcbaldus highresolutionnmrstudiesofantibioticsincellularmembranes
AT ewaswiezewska highresolutionnmrstudiesofantibioticsincellularmembranes
AT eefjanbreukink highresolutionnmrstudiesofantibioticsincellularmembranes
AT markusweingarth highresolutionnmrstudiesofantibioticsincellularmembranes
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