Congestion and Diuretic Resistance in Acute or Worsening Heart Failure

Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore,...

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Autores principales:	Ingibjörg Kristjánsdóttir, Tonje Thorvaldsen, Lars H Lund
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/bd035d6b11864aefbe57fc70c6d15d67
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id	oai:doaj.org-article:bd035d6b11864aefbe57fc70c6d15d67
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spelling	oai:doaj.org-article:bd035d6b11864aefbe57fc70c6d15d672021-12-04T16:03:36ZCongestion and Diuretic Resistance in Acute or Worsening Heart Failure10.15420/cfr.2019.182057-75592057-7540https://doaj.org/article/bd035d6b11864aefbe57fc70c6d15d672020-09-01T00:00:00Zhttps://www.cfrjournal.com/articles/congestion-and-diuretic-resistancehttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore, decongestion is the number one treatment goal. Diuretics are the cornerstone of therapy in AHF, but the treatment effect is challenged by diuretic resistance and poor diuretic response throughout the spectrum of chronic to worsening to acute to post-worsening HF. Adequate dosing and monitoring and evaluation of diuretic effect are important for treatment success. Residual congestion at discharge is a strong predictor of worse outcomes. Therefore, achieving euvolaemia is crucial despite transient worsening renal function.Ingibjörg KristjánsdóttirTonje ThorvaldsenLars H LundRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 6, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
description	Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore, decongestion is the number one treatment goal. Diuretics are the cornerstone of therapy in AHF, but the treatment effect is challenged by diuretic resistance and poor diuretic response throughout the spectrum of chronic to worsening to acute to post-worsening HF. Adequate dosing and monitoring and evaluation of diuretic effect are important for treatment success. Residual congestion at discharge is a strong predictor of worse outcomes. Therefore, achieving euvolaemia is crucial despite transient worsening renal function.
format	article
author	Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund
author_facet	Ingibjörg Kristjánsdóttir Tonje Thorvaldsen Lars H Lund
author_sort	Ingibjörg Kristjánsdóttir
title	Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
title_short	Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
title_full	Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
title_fullStr	Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
title_full_unstemmed	Congestion and Diuretic Resistance in Acute or Worsening Heart Failure
title_sort	congestion and diuretic resistance in acute or worsening heart failure
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/bd035d6b11864aefbe57fc70c6d15d67
work_keys_str_mv	AT ingibjorgkristjansdottir congestionanddiureticresistanceinacuteorworseningheartfailure AT tonjethorvaldsen congestionanddiureticresistanceinacuteorworseningheartfailure AT larshlund congestionanddiureticresistanceinacuteorworseningheartfailure
_version_	1718372757031354368

Congestion and Diuretic Resistance in Acute or Worsening Heart Failure

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