A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA
The reliance on enzymes in SARS-CoV-2 RNA detection imposes limits on transport and storage conditions. Here the authors use non-enzymatic isothermal amplification to detect RNA with no need for reverse transcription.
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Nature Portfolio
2021
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oai:doaj.org-article:bd06ee023a57436bb5b1ecd0d8bd16db2021-12-02T16:35:07ZA non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA10.1038/s41467-021-25387-92041-1723https://doaj.org/article/bd06ee023a57436bb5b1ecd0d8bd16db2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25387-9https://doaj.org/toc/2041-1723The reliance on enzymes in SARS-CoV-2 RNA detection imposes limits on transport and storage conditions. Here the authors use non-enzymatic isothermal amplification to detect RNA with no need for reverse transcription.Mohsen MohammadniaeiMing ZhangJon AshleyUlf Bech ChristensenLennart Jan Friis-HansenRasmus GregersenJan Gorm LisbyThomas Lars BenfieldFinn Erland NielsenJens Henning RasmussenEllen Bøtker PedersenAnne Christine Rye OlingerLærke Tørring KoldingMaryam NaseriTao ZhengWentao WangJan GorodkinYi SunNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Mohsen Mohammadniaei Ming Zhang Jon Ashley Ulf Bech Christensen Lennart Jan Friis-Hansen Rasmus Gregersen Jan Gorm Lisby Thomas Lars Benfield Finn Erland Nielsen Jens Henning Rasmussen Ellen Bøtker Pedersen Anne Christine Rye Olinger Lærke Tørring Kolding Maryam Naseri Tao Zheng Wentao Wang Jan Gorodkin Yi Sun A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| description |
The reliance on enzymes in SARS-CoV-2 RNA detection imposes limits on transport and storage conditions. Here the authors use non-enzymatic isothermal amplification to detect RNA with no need for reverse transcription. |
| format |
article |
| author |
Mohsen Mohammadniaei Ming Zhang Jon Ashley Ulf Bech Christensen Lennart Jan Friis-Hansen Rasmus Gregersen Jan Gorm Lisby Thomas Lars Benfield Finn Erland Nielsen Jens Henning Rasmussen Ellen Bøtker Pedersen Anne Christine Rye Olinger Lærke Tørring Kolding Maryam Naseri Tao Zheng Wentao Wang Jan Gorodkin Yi Sun |
| author_facet |
Mohsen Mohammadniaei Ming Zhang Jon Ashley Ulf Bech Christensen Lennart Jan Friis-Hansen Rasmus Gregersen Jan Gorm Lisby Thomas Lars Benfield Finn Erland Nielsen Jens Henning Rasmussen Ellen Bøtker Pedersen Anne Christine Rye Olinger Lærke Tørring Kolding Maryam Naseri Tao Zheng Wentao Wang Jan Gorodkin Yi Sun |
| author_sort |
Mohsen Mohammadniaei |
| title |
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| title_short |
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| title_full |
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| title_fullStr |
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| title_full_unstemmed |
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA |
| title_sort |
non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of sars-cov-2 rna |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/bd06ee023a57436bb5b1ecd0d8bd16db |
| work_keys_str_mv |
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| _version_ |
1718383778039070720 |