Neuronal ensemble-specific DNA methylation strengthens engram stability

Memories are encoded within neuronal ensembles activated during learning. Here the authors show that DNA methylation within neuronal ensembles contributes to the stability of the memory trace, and increases the likelihood of neuronal ensemble reactivation during retrieval.

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Autores principales: Kubra Gulmez Karaca, Janina Kupke, David V. C. Brito, Benjamin Zeuch, Christian Thome, Dieter Weichenhan, Pavlo Lutsik, Christoph Plass, Ana M. M. Oliveira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bd17ab9d1611495cbd6944c082ec8afa
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