Kimura Disease: Report of a Rare Case

Kimura disease is a rare entity causing subcutaneous swellings and lymphadenopathy, with hardly 120 cases reported worldwide. It is mainly seen in Asian men. Herein, we present a typical case that presents with submandibular mass and persistent eosinophilia. The patient was a 38-year-old man sufferi...

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Autores principales:	Nasrin Moazzen, Farahzad Jabbari, Samaneh Norooziasl, Nazila Ariaee, Amir Amirabadi
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2021
Materias:	kimoura disease neoplasms lymphadenopathy case report Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/bd18fb3acbb340388856030c5e63ece1
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spelling	oai:doaj.org-article:bd18fb3acbb340388856030c5e63ece12021-11-29T10:40:47ZKimura Disease: Report of a Rare Case2008-67092008-668710.30476/mejc.2021.85062.1259https://doaj.org/article/bd18fb3acbb340388856030c5e63ece12021-10-01T00:00:00Zhttps://mejc.sums.ac.ir/article_47368_fc89ace92c117891f6799dc372e397e3.pdfhttps://doaj.org/toc/2008-6709https://doaj.org/toc/2008-6687Kimura disease is a rare entity causing subcutaneous swellings and lymphadenopathy, with hardly 120 cases reported worldwide. It is mainly seen in Asian men. Herein, we present a typical case that presents with submandibular mass and persistent eosinophilia. The patient was a 38-year-old man suffering from left submandibular mass for the last 5 years. It has happened upon a dental infection. Treatment with prednisolone resulted temporary decrease in the size of the lesion, but it wouldn't disappear totally. Since the swelling did not get improved, an excisional biopsy was conducted. The high rate of the eosinophil and histopathology results conducted us to diagnose him with Kimura. Histologically, Kimura disease presents as lymphadenopathy with preserved lymph node architecture and reactive and prominent germinal centers. Dense eosinophilic infiltration of the interfollicular zones, lysis of the follicles, and occasionally microabscesses are seen. Granuloma formations contain infiltration of eosinophils, lymphocytes, plasma cells, and histiocytes. Tissue fibrosis, sclerosis, and vascular proliferation are also present. Vessels remain thin-walled with cubical endothelial cells. This was in line with our patient symptoms.Nasrin MoazzenFarahzad JabbariSamaneh NorooziaslNazila AriaeeAmir AmirabadiShiraz University of Medical Sciencesarticlekimoura diseaseneoplasmslymphadenopathycase reportNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENMiddle East Journal of Cancer , Vol 12, Iss 4, Pp 618-620 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	kimoura disease neoplasms lymphadenopathy case report Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	kimoura disease neoplasms lymphadenopathy case report Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Nasrin Moazzen Farahzad Jabbari Samaneh Norooziasl Nazila Ariaee Amir Amirabadi Kimura Disease: Report of a Rare Case
description	Kimura disease is a rare entity causing subcutaneous swellings and lymphadenopathy, with hardly 120 cases reported worldwide. It is mainly seen in Asian men. Herein, we present a typical case that presents with submandibular mass and persistent eosinophilia. The patient was a 38-year-old man suffering from left submandibular mass for the last 5 years. It has happened upon a dental infection. Treatment with prednisolone resulted temporary decrease in the size of the lesion, but it wouldn't disappear totally. Since the swelling did not get improved, an excisional biopsy was conducted. The high rate of the eosinophil and histopathology results conducted us to diagnose him with Kimura. Histologically, Kimura disease presents as lymphadenopathy with preserved lymph node architecture and reactive and prominent germinal centers. Dense eosinophilic infiltration of the interfollicular zones, lysis of the follicles, and occasionally microabscesses are seen. Granuloma formations contain infiltration of eosinophils, lymphocytes, plasma cells, and histiocytes. Tissue fibrosis, sclerosis, and vascular proliferation are also present. Vessels remain thin-walled with cubical endothelial cells. This was in line with our patient symptoms.
format	article
author	Nasrin Moazzen Farahzad Jabbari Samaneh Norooziasl Nazila Ariaee Amir Amirabadi
author_facet	Nasrin Moazzen Farahzad Jabbari Samaneh Norooziasl Nazila Ariaee Amir Amirabadi
author_sort	Nasrin Moazzen
title	Kimura Disease: Report of a Rare Case
title_short	Kimura Disease: Report of a Rare Case
title_full	Kimura Disease: Report of a Rare Case
title_fullStr	Kimura Disease: Report of a Rare Case
title_full_unstemmed	Kimura Disease: Report of a Rare Case
title_sort	kimura disease: report of a rare case
publisher	Shiraz University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/bd18fb3acbb340388856030c5e63ece1
work_keys_str_mv	AT nasrinmoazzen kimuradiseasereportofararecase AT farahzadjabbari kimuradiseasereportofararecase AT samanehnorooziasl kimuradiseasereportofararecase AT nazilaariaee kimuradiseasereportofararecase AT amiramirabadi kimuradiseasereportofararecase
_version_	1718407424886439936

Kimura Disease: Report of a Rare Case

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