R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.

R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.

The Wnt/β-catenin signaling pathbway controls many important biological processes. R-Spondin (RSPO) proteins are a family of secreted molecules that strongly potentiate Wnt/β-catenin signaling, however, the molecular mechanism of RSPO action is not yet fully understood. We performed an unbiased siRN...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Heinz Ruffner, Joëlle Sprunger, Olga Charlat, Juliet Leighton-Davies, Bianka Grosshans, Adrian Salathe, Svenja Zietzling, Valérie Beck, Maxime Therier, Andrea Isken, Yang Xie, Yue Zhang, Huaixiang Hao, Xiaoying Shi, Dong Liu, Qinhui Song, Ieuan Clay, Gabriele Hintzen, Jan Tchorz, Laure C Bouchez, Gregory Michaud, Peter Finan, Vic E Myer, Tewis Bouwmeester, Jeff Porter, Marc Hild, Fred Bassilana, Christian N Parker, Feng Cong
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/bd2794bcdd5c40a0903a9b2a0d7c9a22
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Documents similaires